Effects of dietary cold-pressed turnip rapeseed oil and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome
Palomäki A, Pohjantähti-Maaroos H, Wallenius M, Kankkunen P, Aro H, Husgafvel S, Pihlava JM, Oksanen K
Lipids in health and disease · 19 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
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- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
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Quién lo pagó
- Financiación
- Financiado por la industria
- Organización sin fines de lucro
- Suomen Kulttuurirahasto
- Organización sin fines de lucro
- Hämeen Rahasto
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2010-12-01 · Lipids Health Dis · vol. 9 · número 1 · pág. 137
- Editorial
- BioMed Central
- Citado
- 28 citas · más que el 77% de estudios similares · 1.3× el promedio de su campo
- Referencias
- 57 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Fatty Acid Research and Health · Nuts composition and effects · Edible Oils Quality and Analysis
- Palabras clave
- Rapeseed, Food science, Polyunsaturated fatty acid, Lipidology, Cholesterol, Clinical chemistry, Blood lipids, Crossover study, Vegetable oil, Medicine, Chemistry, Animal science, Internal medicine, Biology, Biochemistry, Fatty acid
- MeSH
- arteries, humans, brassica napus, butter, fatty acids, omega-3, fatty acids, monounsaturated, lipoproteins, ldl, plant oils, diet, administration, oral, elasticity, adult, aged, middle aged, europe, male, cholesterol, ldl, cholesterol, hdl, metabolic syndrome, rapeseed oil
8 autores
- Ari Palomäki🇫🇮Kanta-Hämeen Keskussairaala
- Hanna Pohjantähti‐Maaroos🇫🇮 · autor de correspondenciaKuopio University Hospital; Kanta-Hämeen Keskussairaala
- Marja Wallenius🇫🇮Kanta-Hämeen Keskussairaala
- Päivi Kankkunen🇫🇮Finnish Institute of Occupational Health; Kanta-Hämeen Keskussairaala
- Heikki Aro🇫🇮Sitra; Finnish Medicines Agency Fimea; Agrifood Research Finland
- Sari Husgafvel🇫🇮Kanta-Hämeen Keskussairaala
- Juha‐Matti Pihlava🇫🇮Agrifood Research Finland
- Kalevi Oksanen🇫🇮Kanta-Hämeen Keskussairaala
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Rapeseed oil is the principal dietary source of monounsaturated and n-3 polyunsaturated fatty acids in the Northern Europe. However, the effect of rapeseed oil on the markers of subclinical atherosclerosis is not known. The purpose of this study was to compare the effects of dietary intake of cold-pressed turnip rapeseed oil (CPTRO) and butter on serum lipids, oxidized LDL and arterial elasticity in men with metabolic syndrome.
Methods
Thirty-seven men with metabolic syndrome completed an open and balanced crossover study. Treatment periods lasted for 6 to 8 weeks and they were separated from each other with an eight-week washout period. Subjects maintained their normal dietary habits and physical activity without major variations. The daily fat adjunct consisted either of 37.5 grams of butter or 35 mL of Virgino R CPTRO. Participants were asked to spread butter on bread on the butter period and to drink CPTRO on the oil period. The fat adjunct was used as such without heating or frying.
Results
Compared to butter, administration of CPTRO was followed by a reduction of total cholesterol by 8% (p < 0.001) and LDL cholesterol by 11% (p < 0.001). The level of oxidized LDL was 16% lower after oil period (p = 0.024). Minimal differences in arterial elasticity were not statistically significant.
Conclusion
Cold-pressed turnip rapeseed oil had favourable effects on circulating LDL cholesterol and oxidized LDL, which may be important in the management of patients at high cardiovascular risk.
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