Effect of intraoral low-level laser therapy on quality of life of patients with head and neck cancer undergoing radiotherapy
Oton-Leite AF, Corrêa de Castro AC, Morais MO, Pinezi JC, Leles CR, Mendonça EF
Head & neck · 46 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
Según 1 financiador declarado.
Publicación
- Publicado
- 2011-04-05 · Head Neck · vol. 34 · número 3 · págs. 398–404
- Editorial
- Wiley
- Citado
- 67 citas · más que el 85% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 47 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Oral health in cancer treatment · Head and Neck Cancer Studies
- Palabras clave
- low-level laser therapy, head and neck cancer, radiotherapy, quality of life, radiotherapy complications, pain, mastication, saliva
- MeSH
- humans, head and neck neoplasms, stomatitis, antineoplastic agents, treatment outcome, neck dissection, cohort studies, recovery of function, quality of life, adult, aged, aged, 80 and over, middle aged, female, male, low-level light therapy, dose fractionation, radiation
6 autores
- Angélica Ferreira Oton‐Leite🇧🇷Universidade Federal de Goiás
- Annelise Carrilho Corrêa de Castro🇧🇷Universidade Federal de Goiás
- Marília Oliveira Morais🇧🇷Universidade Federal de Goiás
- Juliana Castro Dourado Pinezi🇧🇷Hospital Araújo Jorge
- Cláudio Rodrigues Leles🇧🇷Universidade Federal de Goiás
- Elismauro Francisco Mendonça🇧🇷 · autor de correspondenciaUniversidade Federal de Goiás
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Low-level laser therapy has been used to reduce complications of head and neck cancer treatment. The aim was to assess the impact of laser in the quality of life (QOL) of patients receiving radiotherapy.
Methods
Sixty outpatients were randomly assigned into 2 groups. The laser group received applications and the placebo group received sham laser. QOL was assessed using the University of Washington QOL questionnaire. A repeated-measures analysis of variance (ANOVA) was used for comparisons of overall QOL scores and Mann-Whitney test compared changes in domain scores.
Results
A decrease in QOL scores was observed in both groups and the reduction in the laser group was significantly lower (p < .01). Changes in QOL scores regarding pain, chewing, and saliva domains were evident in the placebo group. Both health-related QOL and overall QOL were rated higher by patients who received laser therapy.
Conclusion
Laser therapy reduces the impact of radiotherapy on the QOL of patients with head and neck cancer.
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