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Ensayo controlado aleatorizado2011Financiación no declarada

Effect of different frequencies of creatine supplementation on muscle size and strength in young adults

Candow DG, Chilibeck PD, Burke DG, Mueller KD, Lewis JD

Journal of strength and conditioning research · 16 citas

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2011-04-21 · J Strength Cond Res · vol. 25 · número 7 · págs. 1831–1838
Editorial
Lippincott Williams & Wilkins
Citado
36 citas · más que el 72% de estudios similares · 1.0× el promedio de su campo
Referencias
39 trabajos
Acceso
De pago
Áreas de investigación
Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
Palabras clave
creatine supplementation, dosing frequency, resistance training, muscle thickness, muscle strength, young adults, elbow flexors, leg press strength, sex differences, renal function, urinary microalbumin
MeSH
leg, arm, thorax, muscle, skeletal, humans, creatine, organ size, analysis of variance, double-blind method, physical education and training, dietary supplements, adult, female, male, muscle strength, young adult

5 autores

  • Darren Glenn Candow🇨🇦 · autor de correspondenciaUniversity of Regina; St. Francis Xavier University; University of Saskatchewan
  • Philip David Chilibeck🇨🇦University of Regina; St. Francis Xavier University; University of Saskatchewan
  • Darren G Burke🇨🇦University of Regina; St. Francis Xavier University; University of Saskatchewan
  • Kristie D Mueller🇨🇦University of Regina; St. Francis Xavier University; University of Saskatchewan
  • Jessica D Lewis🇨🇦University of Regina; St. Francis Xavier University; University of Saskatchewan

Resumen

El texto original del estudio, en el idioma en que se publicó.

The purpose was to determine if creatine supplementation, consumed immediately before and immediately after exercise, with different dosing frequency (i.e., 2 or 3 d wk) could enhance the gains in muscle size and strength from resistance training (RT) in young adults. A group of 38 physically active, nonresistance trained university students (21-28 years) was randomly allocated to 1 of 4 groups: CR2 (0.15 g·kg creatine during 2 d wk of RT; 3 sets of 10 repetitions; n = 11, 6 men, 5 women), CR3 (0.10 g·kg creatine during 3 d wk of RT; 2 sets of 10 repetitions; n = 11, 6 men, 5 women;), PLA2 (placebo during 2 d wk of RT; n = 8, 5 men, 3 women), and PLA3 (placebo during 3 d wk of RT; n = 8, 4 men, 4 women) for 6 weeks. Before and after training, measurements were taken for muscle thickness of the elbow and knee flexor and extensor muscle groups (ultrasound), 1-repetition maximumleg press and chest press strength, and kidney function (urinary microalbumin). Repeated-measures analysis of variance showed that strength and muscle thickness increased in all groups with training (p < 0.05). The CR2 (0.6 ± 0.9 cm or 20%; p < 0.05) and CR3 groups (0.4 ± 0.6 cm or 16.4%; p < 0.05) experienced greater change in muscle thickness of the elbow flexors compared to the PLA2 (0.05 ± 0.5 cm or 2.3%) and PLA3 groups (0.13 ± 0.7 cm or 6.3%). Men supplementing with creatine experienced a greater increase in leg press strength (77.3 ± 51.2 kg or 62%) compared to women on creatine (21.3 ± 10 kg or 34%, p < 0.05). We conclude that creatine supplementation during RT has a small beneficial effect on regional muscle thickness in young adults but that giving the creatine over 3 d wk did not differ from giving the same dose over 2 d wk.

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