Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress
De Marchi T, Leal Junior EC, Bortoli C, Tomazoni SS, Lopes-Martins RA, Lopes-Martins RA, Salvador M
Lasers in medical science · 167 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Según 1 financiador declarado.
Publicación
- Publicado
- 2011-07-07 · Lasers Med Sci · vol. 27 · número 1 · págs. 231–236
- Editorial
- Springer Science+Business Media
- Citado
- 234 citas · más que el 98% de estudios similares · 8.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 29 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Exercise and Physiological Responses · Cardiovascular and exercise physiology
- Palabras clave
- low-level laser therapy, exercise performance, oxidative stress, skeletal muscle injury, creatine kinase, lactate dehydrogenase, lipid peroxidation, protein oxidation, superoxide dismutase, catalase, VO2max, time to exhaustion, aerobic threshold, anaerobic threshold, skeletal muscle fatigue, untrained men
- MeSH
- muscle, skeletal, humans, thiobarbituric acid reactive substances, l-lactate dehydrogenase, catalase, superoxide dismutase, exercise test, exercise, cross-over studies, double-blind method, oxidative stress, running, adult, male, creatine kinase, mm form, young adult, low-level light therapy
6 autores
- Thiago De Marchi🇧🇷Universidade de Caxias do Sul
- Ernesto César Pinto Leal‐Junior🇧🇷Universidade Nove de Julho
- Celiana Bortoli🇧🇷Universidade de Caxias do Sul
- Shaiane Silva Tomazoni🇧🇷Universidade de São Paulo
- Rodrigo Álvaro Brandão Lopes‐Martins🇧🇷Universidade de São Paulo; Universidade Nove de Julho
- Mirian Mendonça Salvador🇧🇷 · autor de correspondenciaUniversidade de Caxias do Sul
Resumen
El texto original del estudio, en el idioma en que se publicó.
The aim of this work was to evaluate the effects of low-level laser therapy (LLLT) on exercise performance, oxidative stress, and muscle status in humans. A randomized double-blind placebo-controlled crossover trial was performed with 22 untrained male volunteers. LLLT (810 nm, 200 mW, 30 J in each site, 30 s of irradiation in each site) using a multi-diode cluster (with five spots - 6 J from each spot) at 12 sites of each lower limb (six in quadriceps, four in hamstrings, and two in gastrocnemius) was performed 5 min before a standardized progressive-intensity running protocol on a motor-drive treadmill until exhaustion. We analyzed exercise performance (VO(2 max), time to exhaustion, aerobic threshold and anaerobic threshold), levels of oxidative damage to lipids and proteins, the activities of the antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT), and the markers of muscle damage creatine kinase (CK) and lactate dehydrogenase (LDH). Compared to placebo, active LLLT significantly increased exercise performance (VO(2 max) p = 0.01; time to exhaustion, p = 0.04) without changing the aerobic and anaerobic thresholds. LLLT also decreased post-exercise lipid (p = 0.0001) and protein (p = 0.0230) damages, as well as the activities of SOD (p = 0.0034), CK (p = 0.0001) and LDH (p = 0.0001) enzymes. LLLT application was not able to modulate CAT activity. The use of LLLT before progressive-intensity running exercise increases exercise performance, decreases exercise-induced oxidative stress and muscle damage, suggesting that the modulation of the redox system by LLLT could be related to the delay in skeletal muscle fatigue observed after the use of LLLT.
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