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Ensayo controlado aleatorizado2012Financiado por la industria

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Effects of caffeine on alcohol-related changes in behavioural control and perceived intoxication in light caffeine consumers

Attwood AS, Rogers PJ, Ataya AF, Adams S, Munafò MR

Psychopharmacology · 35 citas

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Financiado por la industria

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiado por la industria
Empresa
GlaxoSmithKline
Universidad u hospital
University of Bristol

Según 2 financiadores declarados.

Publicación

Publicado
2011-12-15 · Psychopharmacology (Berl) · vol. 221 · número 4 · págs. 551–560
Editorial
Springer Science+Business Media
Citado
54 citas · más que el 95% de estudios similares · 4.6× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
34 trabajos
Acceso
De pago
Áreas de investigación
Coffee research and impacts · Substance Abuse Treatment and Outcomes · Alcohol Consumption and Health Effects
Palabras clave
caffeine, alcohol, behavioral control, perceived intoxication, reaction time, Stroop task, go/no-go task, stop-signal task, alcohol craving, anxiety, mood, stimulation, alcohol-related harm
MeSH
humans, alcoholic intoxication, ethanol, caffeine, central nervous system depressants, central nervous system stimulants, double-blind method, alcohol drinking, psychomotor performance, reaction time, alcoholic beverages, adolescent, adult, female, male, young adult

5 autores

  • Angela Suzanne Attwood🇬🇧 · autor de correspondenciaUniversity of Bristol
  • Peter J. Rogers🇬🇧University of Bristol
  • Alia F. Ataya🇬🇧University of Bristol
  • Sally H. Adams🇬🇧University of Bristol
  • Marcus Robert Munafo🇬🇧University of Bristol

Resumen

El texto original del estudio, en el idioma en que se publicó.

Rationale

Caffeinated alcoholic beverages have been associated with increased risk of alcohol-related harms. However, few studies have examined these combined effects on behavioural control, which is believed to underlie many of the negative effects of alcohol consumption. In addition, studies have often omitted subjective measures, and none have directly assessed the role of caffeine consumer history.

Objectives

To examine the combined effects of alcohol and caffeine on measures of behavioural control and perceived intoxication in abstinent, light caffeine consumers.

Methods

Participants (n = 28; 50% male) attended four sessions at which they consumed one of the following beverages in a randomised order: placebo, alcohol alone (0.6 g/kg), caffeine alone (2.0 mg/kg), and alcohol/caffeine. They completed measures of mood, intoxication, anxiety and alcohol craving before and after a task battery comprising measures of behavioural control and reaction time performance.

Results

Caffeine attenuated alcohol-related performance deficits on stop-signal accuracy, had no effect on go-no-go performance deficits, and worsened accuracy on the Stroop task. Caffeine did not influence absolute changes in perceived intoxication but there was suggestion that caffeine may have changed the nature of intoxication with increases in stimulation.

Conclusions

Caffeine appears to have mixed effects on alcohol intoxication that are task-dependent. We found increased stimulation in the alcohol/caffeine condition, supporting the contention that caffeinated alcoholic beverages enable an individual to drink for longer. Future research should model real world drinking behaviour by examining how these effects change across multiple drink administrations.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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