Low-level laser therapy improves visual acuity in adolescent and adult patients with amblyopia
Ivandic BT, Ivandic T
Photomedicine and laser surgery · 28 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2012-01-11 · Photomed Laser Surg · vol. 30 · número 3 · págs. 167–171
- Editorial
- Mary Ann Liebert, Inc.
- Citado
- 45 citas · más que el 74% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 11 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Ocular and Laser Science Research · Ophthalmology and Visual Impairment Studies
- Palabras clave
- low-level laser therapy, amblyopia, visual acuity, strabismus, refractive error, adult amblyopia, multifocal visual evoked potentials
- MeSH
- humans, amblyopia, strabismus, refractive errors, ophthalmoscopy, treatment outcome, follow-up studies, single-blind method, radiation dosage, age factors, sex factors, dose-response relationship, radiation, evoked potentials, visual, visual acuity, time factors, adolescent, adult, aged, middle aged, patient satisfaction, female, male, young adult, low-level light therapy
2 autores
- Boris Ivandic🇩🇪 · autor de correspondenciaHeidelberg University
- Tomislav Ivandić
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
The purpose of this study was to examine the effects of low-level laser therapy (LLLT) on visual acuity in adolescent and adult patients with amblyopia.
Background data
Currently, amblyopia can be treated successfully only in children.
Methods
In this single-blinded, placebo-controlled study, 178 patients (mean age 46.8 years) with amblyopia caused by ametropia (110 eyes) or strabismus (121 eyes) were included. For LLLT, the area of the macula was irradiated through the conjunctiva from 1 cm distance for 30 sec with laser light (780 nm, 292 Hz, 1:1 duty cycle; average power 7.5 mW; spot area 3 mm(2)). The treatment was repeated on average 3.5 times, resulting in a mean total dose of 0.77 J/cm(2). No occlusion was applied, and no additional medication was administered. Best corrected distant visual acuity was determined using Snellen projection optotypes. In 12 patients (12 eyes), the multifocal visual evoked potential (M-VEP) was recorded. A control group of 20 patients (20 eyes) received mock treatment.
Results
Visual acuity improved in ∼90% of the eyes treated with LLLT (p<0.001), increasing by three or more lines in 56.2% and 53.6% of the eyes with amblyopia caused by ametropia and strabismus, respectively. The treatment effect was maintained for at least 6 months. The mean M-VEP amplitude increased by 1207 nV (p<0.001) and mean latency was reduced by 7 msec (p=0.14). No changes were noted in the control group.
Conclusions
LLLT led to a significant improvement in visual acuity in adolescent and adult patients with amblyopia caused by ametropia or strabismus.
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