Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies
Larsson SC, Wolk A
British journal of cancer · 165 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- Swedish Cancer Foundation
- Universidad u hospital
- Karolinska Institutet
Según 2 financiadores declarados.
Publicación
- Publicado
- 2012-01-01 · Br J Cancer · vol. 106 · número 3 · págs. 603–607
- Editorial
- Springer Nature
- Citado
- 282 citas · más que el 94% de estudios similares · 2.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 34 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-SA
- Áreas de investigación
- Pancreatic and Hepatic Oncology Research · Pancreatitis Pathology and Treatment · Nutrition and Health in Aging
- Palabras clave
- Pancreatic cancer, Meta-analysis, Medicine, Prospective cohort study, Consumption (sociology), Cancer, Internal medicine, Processed meat, Oncology, Risk factor, Environmental health, Food science, Biology
- MeSH
- animals, cattle, sheep, swine, humans, pancreatic neoplasms, diet surveys, risk factors, prospective studies, meat, meat products, adult, aged, middle aged, united states, japan, europe, female, male, surveys and questionnaires
2 autores
- Susanna C. Larsson🇸🇪 · autor de correspondenciaKarolinska Institutet
- Alicja Wolk🇸🇪Karolinska Institutet
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Whether red and processed meat consumption is a risk factor for pancreatic cancer remains unclear. We conducted a meta-analysis to summarise the evidence from prospective studies of red and processed meat consumption and pancreatic cancer risk.
Methods
Relevant studies were identified by searching PubMed and EMBASE databases through November 2011. Study-specific results were pooled using a random-effects model.
Results
Eleven prospective studies, with 6643 pancreatic cancer cases, were included in the meta-analysis. An increase in red meat consumption of 120 g per day was associated with an overall relative risk (RR) of 1.13 (95% confidence interval (CI)=0.93-1.39; P(heterogeneity)<0.001). Red meat consumption was positively associated with pancreatic cancer risk in men (RR=1.29; 95% CI=1.08-1.53; P(heterogeneity)=0.28; five studies), but not in women (RR=0.93; 95% CI=0.74-1.16; P(heterogeneity)=0.21; six studies). The RR of pancreatic cancer for a 50 g per day increase in processed meat consumption was 1.19 (95% CI=1.04-1.36; P(heterogeneity)=0.46).
Conclusion
Findings from this meta-analysis indicate that processed meat consumption is positively associated with pancreatic cancer risk. Red meat consumption was associated with an increased risk of pancreatic cancer in men. Further prospective studies are needed to confirm these findings.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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