Broccoli sprouts powder could improve serum triglyceride and oxidized LDL/LDL-cholesterol ratio in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial
Bahadoran Z, Mirmiran P, Hosseinpanah F, Rajab A, Asghari G, Azizi F
Diabetes research and clinical practice · 82 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2012-02-10 · Diabetes Res Clin Pract · vol. 96 · número 3 · págs. 348–354
- Editorial
- Elsevier BV
- Citado
- 122 citas · más que el 93% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 38 trabajos
- Acceso
- De pago
- Áreas de investigación
- Genomics, phytochemicals, and oxidative stress · Diabetes, Cardiovascular Risks, and Lipoproteins · Natural Antidiabetic Agents Studies
- Palabras clave
- type 2 diabetes, serum triglycerides, oxidized LDL, LDL cholesterol, atherogenic index of plasma, HDL cholesterol, lipid profile, cardiovascular risk factors, dietary supplementation, bioactive compounds
- MeSH
- humans, brassica, diabetes mellitus, type 2, blood glucose, lipoproteins, ldl, plant preparations, powders, anticholesteremic agents, antioxidants, phytotherapy, double-blind method, oxidative stress, dose-response relationship, drug, middle aged, female, male
6 autores
- Zahra Bahadoran🇮🇷 · autor de correspondenciaResearch Institute for Endocrine Sciences; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
- Parvin Mirmiran🇮🇷 · autor de correspondenciaNational Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences
- Farhad Hosseinpanah🇮🇷 · autor de correspondenciaResearch Institute for Endocrine Sciences; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
- Asadolah Rajab
- Golaleh Asghari🇮🇷 · autor de correspondenciaResearch Institute for Endocrine Sciences; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
- Fereidoun Azizi🇮🇷 · autor de correspondenciaResearch Institute for Endocrine Sciences; Shahid Beheshti University; Shahid Beheshti University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and aims
In this study, broccoli sprout powder (BSP), a good source of bioactive components, was used as supplementary treatment in type 2 diabetic patients.
Methods
This randomized clinical trial included 81 patients with type 2 diabetes. Participants were randomly assigned to consume 10g/d BSP (group A), 5g/d BSP (group B), or the placebo (group C), each for 4 weeks. Fasting blood glucose (FBS), total cholesterol (TC), triglyceride concentration (TG), LDL-C, HDL-C, and oxidized-LDL were measured at baseline and 4 weeks after treatment. The ratios of OX-LDL/LDL, atherogenic index of plasma (AIP; log TG/HDL), TC/HDL and LDL/HDL were calculated as cardiovascular risk factors parameters, at baseline and 4 weeks after treatment.
Results
Seventy-two patients completed the study; n=23, 26 and 23 for groups A, B and C, respectively. After 4 weeks, BSP in dose of 10g/d, significantly decreased serum triglycerides, OX-LDL/LDL ratio and AIP (p<0.05 for treatment effect). HDL-C concentration was significantly higher (p<0.01 for treatment) in group A as compared with group B and placebo.
Conclusions
BSP as supplementary treatment in type 2 diabetes could have favorable effects on lipid profiles and OX-LDL/LDL ratio, as risk factors for cardiovascular disease.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.