Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task
Foxe JJ, Morie KP, Laud PJ, Rowson MJ, de Bruin EA, Kelly SP, Kelly SP
Neuropharmacology · 67 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2012-02-02 · Neuropharmacology · vol. 62 · número 7 · págs. 2320–2327
- Editorial
- Elsevier BV
- Citado
- 106 citas · más que el 95% de estudios similares · 4.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 48 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Sleep and Work-Related Fatigue · Mind wandering and attention
- Palabras clave
- caffeine, theanine, vigilant attention, sustained attention, Sustained Attention to Response Task, alpha oscillations, time on task, error rate, tea, combination supplementation, EEG
- MeSH
- humans, caffeine, glutamates, drug combinations, treatment outcome, cross-over studies, double-blind method, psychomotor performance, arousal, attention, reaction time, time factors, adolescent, adult, female, male, young adult
6 autores
- John J. Foxe🇺🇸 · autor de correspondenciaNathan Kline Institute for Psychiatric Research; City College of New York; Albert Einstein College of Medicine; City University of New York
- Kristen P. Morie🇺🇸Nathan Kline Institute for Psychiatric Research; City College of New York; Albert Einstein College of Medicine; City University of New York
- Peter J. Laud🇬🇧University of Sheffield
- Matthew J. Rowson🇬🇧Unilever (United Kingdom)
- Eveline A. de Bruin🇳🇱Unilever Research and Development Vlaardingen
- Simon P. Kelly🇺🇸City College of New York; City University of New York
Resumen
El texto original del estudio, en el idioma en que se publicó.
Caffeine and L-theanine, both naturally occurring in tea, affect the ability to make rapid phasic deployments of attention to locations in space as reflected in behavioural performance and alpha-band oscillatory brain activity (8-14 Hz). However, surprisingly little is known about how these compounds affect an aspect of attention that has been more popularly associated with tea, namely vigilant attention: the ability to maintain focus on monotonous tasks over protracted time-periods. Twenty-seven participants performed the Sustained Attention to Response Task (SART) over a two-hour session on each of four days, on which they were administered caffeine (50 mg), theanine (100 mg), the combination, or placebo in a double-blind, randomized, cross-over fashion. Concurrently, we recorded oscillatory brain activity through high-density electroencephalography (EEG). We asked whether either compound alone, or both in combination, would affect performance of the task in terms of reduced error rates over time, and whether changes in alpha-band activity would show a relationship to such changes in performance. When treated with placebo, participants showed a rise in error rates, a pattern that is commonly observed with increasing time-on-task, whereas after caffeine and theanine ingestion, error rates were significantly reduced. The combined treatment did not confer any additional benefits over either compound alone, suggesting that the individual compounds may confer maximal benefits at the dosages employed. Alpha-band oscillatory activity was significantly reduced on ingestion of caffeine, particularly in the first hour. This effect was not changed by addition of theanine in the combined treatment. Theanine alone did not affect alpha-band activity.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.