The safety of cruciferous plants in humans: a systematic review
Scott O, Galicia-Connolly E, Adams D, Surette S, Vohra S, Yager JY
Journal of biomedicine & biotechnology · 7 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- Heart and Stroke Foundation of Canada
- Organización sin fines de lucro
- Alva Foundation
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2012-01-01 · J Biomed Biotechnol · vol. 2012 · págs. 1–28
- Editorial
- Hindawi Publishing Corporation
- Citado
- 21 citas · más que el 16% de estudios similares · 0.1× el promedio de su campo
- Referencias
- 83 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Genomics, phytochemicals, and oxidative stress · Vitamin C and Antioxidants Research · Herbal Medicine Research Studies
- Palabras clave
- Cruciferous vegetables, Adverse effect, Medicine, Observational study, Internal medicine, Cancer
- MeSH
- humans, brassicaceae, plant extracts
6 autores
- Ori Scott🇨🇦University of Alberta; Stollery Children's Hospital
- Elaine Galicia-Connolly🇨🇦University of Alberta Hospital
- Denise L. C. Adams🇨🇦University of Alberta Hospital
- Soleil Surette🇨🇦University of Alberta Hospital
- Sunita Vohra🇨🇦University of Alberta; University of Alberta Hospital
- Jerome Y. Yager🇨🇦 · autor de correspondenciaUniversity of Alberta; Stollery Children's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Some cruciferous plants may serve as preventive treatments for several medical conditions; our objective was to systematically investigate their safety in humans. Four electronic databases were searched, and, of 10,831 references identified, 50 were included. Data were extracted by two independent reviewers, whereafter the association between interventions and adverse events was assessed. Adverse events in 53 subjects were identified through clinical trials; of these, altered drug metabolism was rated as certainly/likely caused by cruciferous plants. Adverse events in 1247 subjects were identified through observational studies, of which none received high causality ratings. Adverse events in 35 subjects were identified through case reports, of which allergies and warfarin resistance were rated as certainly/likely caused by cruciferous plants. We conclude that cruciferous plants are safe in humans, with the exception of allergies. Individuals treated with warfarin should consult their physician. Further investigation of uses of cruciferous plants in preventative medicine is warranted.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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