Dietary methods and biomarkers of omega 3 fatty acids: a systematic review
Serra-Majem L, Nissensohn M, Øverby NC, Fekete K
The British journal of nutrition · 93 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Sin resultado de salud
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Universidad de Las Palmas de Gran Canaria
Según 1 financiador declarado.
Publicación
- Publicado
- 2012-05-17 · Br J Nutr · vol. 107 · número S2 · págs. S64–S76
- Editorial
- Cambridge University Press
- Citado
- 118 citas · más que el 68% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 87 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Fatty Acid Research and Health · Nutritional Studies and Diet · Aquaculture Nutrition and Growth
- Palabras clave
- omega-3 fatty acids, long-chain polyunsaturated fatty acids, dietary assessment, dietary questionnaire, biomarkers, docosahexaenoic acid, eicosapentaenoic acid, subcutaneous adipose tissue, serum lipids, plasma phospholipids, n-3 PUFA supplementation
- MeSH
- humans, lipids, dietary fats, fatty acids, omega-3, docosahexaenoic acids, diet, nutrition assessment, nutritional status, reference values, dietary supplements, subcutaneous fat, validation studies as topic, biomarkers
4 autores
- Lluís Serra‐Majem🇪🇸 · autor de correspondenciaUniversidad de Las Palmas de Gran Canaria; Parc Científic de Barcelona; Universitat de Barcelona
- Mariela Nissensohn🇪🇸Universidad de Las Palmas de Gran Canaria
- Nina Cecilie Øverby🇳🇴University of Agder
- Katalin Fekete🇭🇺University of Pecs
Resumen
El texto original del estudio, en el idioma en que se publicó.
The aims of the present study were to review the validity of dietary methods used to measure the usual long chain (LC) omega-3 polyunsaturated fatty acid (n-3 PUFA) intake of a population and to assess the usefulness of different biomarkers of n-3 PUFA in healthy humans. Two systematic literature searches were conducted until May 2011 to update previous systematic reviews. The first literature search aimed to find studies validating the methodology used for measuring the dietary intake of n-3 PUFA. The second search aimed to find human intervention studies in which n-3 PUFA status changed after 2 weeks of n-3 PUFA supplementation. Sixteen studies were identified for inclusion in the first review. Correlation coefficients between fatty acids in subcutaneous fat or blood lipids and dietary intake of n-3 PUFA from different questionnaires were similar. Subcutaneous fat has been reported as the best reference method for some authors, and these studies showed moderate correlation coefficients with no dietary intake method being superior to any other. As for the evaluation of biomarkers of docosahexaenoic acid (DHA, 22 : 6 n-3) and eicosapentaenoic acid (EPA, 20 : 5n-3) status in response to supplementation, the new search reaffirmed and reinforced the evidence supporting that plasma phospholipid DHA, erythrocyte DHA, and platelet DHA were all effective and robust biomarkers of DHA status. Our findings only confirmed earlier studies and did not provide evidence for reaching new conclusions.
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