A randomized trial of the effects of an almond-enriched, hypocaloric diet in the treatment of obesity
Foster GD, Shantz KL, Vander Veur SS, Oliver TL, Lent MR, Virus A, Szapary PO, Rader DJ, Zemel BS, Gilden-Tsai A
The American journal of clinical nutrition · 72 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Autores
- Al menos un autor declara un vínculo económico con la industria
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2012-06-29 · Am J Clin Nutr · vol. 96 · número 2 · págs. 249–254
- Editorial
- Elsevier BV
- Citado
- 99 citas · más que el 97% de estudios similares · 6.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 39 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Diet and metabolism studies
- Palabras clave
- almond, hypocaloric diet, obesity, weight loss, behavioral weight management, cardiovascular risk factors, lipid profile, cholesterol, triglycerides, body composition, overweight adults
- MeSH
- humans, prunus, nuts, cardiovascular diseases, obesity, body weight, triglycerides, body mass index, treatment outcome, caloric restriction, diet, risk factors, body composition, energy intake, adult, middle aged, female, male, overweight, cholesterol, ldl, cholesterol, hdl
10 autores
- Gary D. Foster🇺🇸Temple University
- Kerri Leh Shantz
- Stephanie S. Vander Veur
- Tracy L. Oliver
- Michelle R. Lent
- Amy Virus
- Philippe O. Szapary
- Daniel James Rader
- Babette S. Zemel
- Adam Gilden Tsai
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Increased consumption of nuts has been advocated because of their health benefits, but the role of nuts in the treatment of obesity is unclear given their high energy density.
Objective
This study was designed to evaluate the effects of a hypocaloric, almond-enriched diet (AED) compared with a hypocaloric nut-free diet (NFD) on body weight and cardiovascular disease risk factors in the context of an 18-mo behavioral weight-management program.
Design
Overweight and obese individuals [n = 123; age = 46.8 y, BMI (in kg/m(2)) = 34.0] were randomly assigned to consume an AED or NFD and instructed in traditional behavioral methods of weight control. Anthropometric and metabolic measurements were made at baseline, 6 mo, and 18 mo.
Results
Those in the AED group lost slightly but significantly less weight than did those in the NFD group at 6 mo (-5.5 compared with -7.4 kg; P = 0.04), but there were no differences at 18 mo. No significant differences in body composition were found between the groups at 6 or 18 mo. The AED, compared with the NFD, was associated with greater reductions in total cholesterol (P = 0.03), total:HDL cholesterol (P = 0.02), and triglycerides (P = 0.048) at 6 mo, and no differences were observed between the groups at 18 mo.
Conclusions
The AED and NFD groups experienced clinically significant and comparable weight loss at 18 mo. Despite smaller weight loss in the AED group at 6 mo, the AED group experienced greater improvements in lipid profiles. This trial was registered at clinicaltrials.gov as NCT00194428.
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