Financiado en parte por Novo Nordisk Fonden
High intakes of protein and processed meat associate with increased incidence of type 2 diabetes
Ericson U, Sonestedt E, Gullberg B, Hellstrand S, Hindy G, Wirfält E, Orho-Melander M
The British journal of nutrition · 86 citas
Etiquetas de revisión
Financiado por la industriaSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- Novo Nordisk Fonden
- Gobierno
- Medical Research Council
Según 2 financiadores declarados.
Publicación
- Publicado
- 2012-08-01 · Br J Nutr · vol. 109 · número 6 · págs. 1143–1153
- Editorial
- Cambridge University Press
- Citado
- 119 citas · más que el 94% de estudios similares · 3.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 48 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Diet and metabolism studies · Nutritional Studies and Diet · Nutrition, Genetics, and Disease
- Palabras clave
- Medicine, Type 2 diabetes, Diabetes mellitus, Hazard ratio, Incidence (geometry), Cohort study, Cohort, Population, Internal medicine, Animal science, Endocrinology, Biology, Confidence interval, Environmental health
- MeSH
- animals, humans, diabetes mellitus, type 2, dietary carbohydrates, dietary fats, dietary proteins, body mass index, exercise, diet, risk factors, cohort studies, prospective studies, body composition, dietary fiber, meat products, aged, middle aged, educational status, female, male, waist circumference
7 autores
- Ulrika Ericson🇸🇪 · autor de correspondenciaLund University
- Emily Sonestedt🇸🇪Lund University
- Bo Gullberg🇸🇪Lund University
- Sophie Hellstrand🇸🇪Lund University
- George Hindy🇸🇪Lund University
- Elisabet Wirfält🇸🇪Lund University
- Marju Orho‐Melander🇸🇪Lund University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Diets high in protein have shown positive effects on short-term weight reduction and glycaemic control. However, the understanding of how dietary macronutrient composition relates to long-term risk of type 2 diabetes is limited. The aim of the present study was to examine intakes of macronutrients, fibre and protein sources in relation to incident type 2 diabetes. In total, 27 140 individuals, aged 45-74 years, from the population-based Malmö Diet and Cancer cohort, were included. Dietary data were collected with a modified diet history method, including registration of cooked meals. During 12 years of follow-up, 1709 incident type 2 diabetes cases were identified. High protein intake was associated with increased risk of type 2 diabetes (hazard ratio (HR) 1.27 for highest compared with lowest quintile; 95 % CI 1.08, 1.49; P for trend = 0.01). When protein consumption increased by 5 % of energy at the expense of carbohydrates (HR 1.20; 95 % CI 1.09, 1.33) or fat (HR 1.21; 95 % CI 1.09, 1.33), increased diabetes risk was observed. Intakes in the highest quintiles of processed meat (HR 1.16; 95 % CI 1.00, 1.36; P for trend = 0.01) and eggs (HR 1.21; 95 % CI 1.04, 1.41; P for trend = 0.02) were associated with increased risk. Intake of fibre-rich bread and cereals was inversely associated with type 2 diabetes (HR 0.84; 95 % CI 0.73, 0.98; P for trend = 0.004). In conclusion, results from the present large population-based prospective study indicate that high protein intake is associated with increased risk of type 2 diabetes. Replacing protein with carbohydrates may be favourable, especially if fibre-rich breads and cereals are chosen as carbohydrate sources.
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