Effects of a rapeseed oil-enriched hypoenergetic diet with a high content of α-linolenic acid on body weight and cardiovascular risk profile in patients with the metabolic syndrome
Baxheinrich A, Stratmann B, Lee-Barkey YH, Tschoepe D, Wahrburg U
The British journal of nutrition · 72 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Universidade Federal de Ouro Preto
Según 1 financiador declarado.
Publicación
- Publicado
- 2012-08-16 · Br J Nutr · vol. 108 · número 4 · págs. 682–691
- Editorial
- Cambridge University Press
- Citado
- 91 citas · más que el 93% de estudios similares · 3.6× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 60 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Diet and metabolism studies · Diet, Metabolism, and Disease · Nutritional Studies and Diet
- Palabras clave
- Rapeseed, Food science, Metabolic syndrome, Linolenic acid, Body weight, Chemistry, Medicine, Obesity, Animal science, Endocrinology, Biochemistry, Fatty acid, Biology, Linoleic acid
- MeSH
- humans, brassica rapa, seeds, cardiovascular diseases, hypertension, weight loss, alpha-linolenic acid, fatty acids, monounsaturated, plant oils, diet, reducing, prevalence, risk factors, feasibility studies, patient compliance, adult, middle aged, patient dropouts, germany, female, male, hyperlipidemias, metabolic syndrome, rapeseed oil
5 autores
- Andrea Baxheinrich🇩🇪 · autor de correspondenciaFH Münster
- Bernd Stratmann🇩🇪Heart and Diabetes Center North Rhine-Westphalia; Ruhr University Bochum
- Young Hee Lee-Barkey🇩🇪Heart and Diabetes Center North Rhine-Westphalia; Ruhr University Bochum
- Diethelm Tschoepe🇩🇪Heart and Diabetes Center North Rhine-Westphalia; Ruhr University Bochum
- Ursel Wahrburg🇩🇪FH Münster
Resumen
El texto original del estudio, en el idioma en que se publicó.
In therapy of the metabolic syndrome, the optimal dietary approach with regard to its macronutrient composition and metabolically favourable food components, such as the plant-derived n-3 fatty acid α-linolenic acid (ALA), is still a matter of debate. We investigated the effects of a hypoenergetic diet with low energy density (ED) enriched in rapeseed oil, resulting in high MUFA content and an ALA intake of 3.5 g/d on body weight and cardiovascular risk profile in eighty-one patients with the metabolic syndrome in comparison with an olive oil diet rich in MUFA, but with a low ALA content. After a 6-month dietary intervention, body weight was significantly reduced in the rapeseed oil and olive oil groups ( -7.8 v. -6.0 kg; P < 0.05). There were significant decreases in systolic blood pressure, total cholesterol and LDL-cholesterol, and insulin levels in both groups (P < 0.05). For all of these changes, no inter-group differences were observed. After the rapeseed oil diet, diastolic blood pressure declined more than after the olive oil diet (P < 0.05 for time × group interaction). Furthermore, concentrations of serum TAG were significantly reduced after the high ALA intake, but not in the low ALA group (P < 0.05 for time × group interaction). In conclusion, our dietary food pattern with a low ED and high intakes of MUFA and ALA may be a practical approach for long-term dietary treatment in patients with the metabolic syndrome, leading to weight reduction and an improvement in the overall cardiovascular risk profile.
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