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Ensayo clínico controlado2012Financiación no declarada

Low-level lasers as an adjunct in periodontal therapy in patients with diabetes mellitus

Obradović R, Kesić L, Mihailović D, Jovanović G, Antić S, Brkić Z

Diabetes technology & therapeutics · 28 citas

Etiquetas de revisión

Financiación no declarada

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Cómo se estudió

Diseño
Ensayo clínico controlado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2012-09-01 · Diabetes Technol Ther · vol. 14 · número 9 · págs. 799–803
Editorial
Mary Ann Liebert, Inc.
Citado
40 citas · más que el 81% de estudios similares · 1.4× el promedio de su campo
Referencias
41 trabajos
Acceso
Acceso abierto (copia en repositorio)
Áreas de investigación
Laser Applications in Dentistry and Medicine · Oral microbiology and periodontitis research · Photodynamic Therapy Research Studies
Palabras clave
Medicine, Periodontitis, Dentistry, Diabetes mellitus, Scaling and root planing, Oral hygiene, Laser therapy, Periodontology, Inflammation, Chronic periodontitis, Internal medicine, Laser
MeSH
mouth mucosa, dental plaque, humans, gingivitis, periodontitis, diabetes mellitus, type 1, diabetes mellitus, type 2, diabetes complications, treatment outcome, oral hygiene, dental scaling, root planing, adult, middle aged, female, male, patient education as topic, low-level light therapy, glycated hemoglobin

6 autores

  • Radmila R. Obradović🇷🇸 · autor de correspondenciaUniversity of Nis
  • Ljiljana G. Kesić🇷🇸University of Nis
  • Dragan Mihailovic🇷🇸University of Nis
  • Goran S. Jovanovic🇷🇸University of Nis
  • Slobodan Antić🇷🇸University of Nis
  • Zlata Brkić🇷🇸Military Medical Academy; University of Belgrade

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Diabetes mellitus (DM) increases the risk of periodontitis, and severe periodontitis often coexists with severe DM. The proposed dual pathway of tissue destruction suggests that control of chronic periodontal infection and gingival inflammation is essential for achieving long-term control of DM. The purpose this study is to evaluate the effects of low-level laser therapy (LLLT) by exfoliative cytology in patients with DM and gingival inflammation.

Subjects and methods

Three hundred patients were divided in three equal groups: Group 1 consisted of patients with periodontitis and type 1 DM, Group 2 of patients with periodontitis and type 2 DM, and Group 3 of patients with periodontitis (control group). After oral examination, smears were taken from gingival tissue, and afterward all of the patients received oral hygiene instructions, removal of dental plaque, and full-mouth scaling and root planing. A split-mouth design was applied; on the right side of jaws GaAlAs LLLT (670 nm, 5 mW, 14 min/day) (model Mils 94; Optica Laser, Sofia, Bulgaria) was applied for five consecutive days. After the therapy was completed, smears from both sides of jaws were taken. The morphometric analysis was done using the National Institutes of Health Image software program and a model NU2 microscope (Carl Zeiss, Jena, Germany).

Results

Investigated parameters were significantly lower after therapy compared with values before therapy. After therapy on the side subjected to LLLT, there was no significantly difference between patients with DM and the control group.

Conclusions

It can be concluded that LLLT as an adjunct in periodontal therapy reduces gingival inflammation in patients with DM and periodontitis.

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