Effect of subgingival application of topical ozonated olive oil in the treatment of chronic periodontitis: a randomized, controlled, double blind, clinical and microbiological study
Patel PV, Patel A, Kumar S, Holmes JC
Minerva stomatologica · 34 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2012-09-01 · Minerva Stomatol · vol. 61 · número 9 · págs. 381–98
- Editorial
- National Institutes of Health
- Citado
- 43 citas · más que el 74% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 0 trabajos
- Acceso
- De pago
- Áreas de investigación
- Medical and Biological Ozone Research · Oral microbiology and periodontitis research · Periodontal Regeneration and Treatments
- Palabras clave
- ozonated olive oil, chronic periodontitis, scaling and root planing, adjunctive periodontal therapy, chlorhexidine, subgingival plaque, periodontal pathogens, dentin hypersensitivity, clinical attachment level, probing depth, dental pain
- MeSH
- gingiva, humans, plant oils, administration, topical, double-blind method, adult, female, male, chronic periodontitis, olive oil
4 autores
- P V Patel
- Ashwin P. Patel
- Sheela Kumar
- J C Holmes
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim
The aim of this paper was to evaluate the efficacy of ozonated olive oil as a monotherapy and an adjunct to scaling and root planing in the treatment of chronic periodontitis
Methods
A split mouth, double-blinded, randomized controlled clinical trial was conducted on 20 subjects diagnosed with chronic periodontitis. Quadrants of each subject were randomly assigned to four groups and treated accordingly: Group A, scaling and root planing (SRP): Group B, topical ozonated olive oil (OZO) as an adjunct to scaling and root planing: Group C, topical ozonated olive oil as a monotherapy and: Group D, topical chlorhexidine gel as a monotherapy. The quadrants were analyzed clinically by plaque index, gingival index, sulcus bleeding index, probing pocket depth, and clinical attachment level at baseline, 2, 4, 6 and 8 weeks of time intervals. The subjects were also analyzed for perceived pain, discomfort or tooth hypersensitivity (quadrant wise) on a Visual Analogue Scale (VAS). Additionally, subgingival plaque samples were collected from the two predetermined sites of each quadrant at baseline, 4 and 8 weeks for the analysis of total bacterial counts (TBCs) and the detection of frequency of eight putative periodontopathogens by polymerase chain reaction (PCR) method.
Results
The adjunctive use of the OZO with SRP resulted in a significant improvement (P<0.001) of clinical parameters as well as microbiological parameters over the time and in comparison to the control groups. The OZO as monotherapy also showed a significant improvement (P<0.001) in clinical parameters as well as microbiological parameters over the time without any documented side effects. However, there was a significant increase (P<0.05) in dentinal hypersensitivity following OZO as an adjunct to scaling and root planing therapy.
Conclusion
The OZO, as an adjunctive therapy as well as a mono-therapy is efficient in improving periodontal conditions.
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