Efficacy of low-level laser therapy in the management of orthodontic pain: a systematic review and meta-analysis
He WL, Li CJ, Liu ZP, Sun JF, Hu ZA, Yin X, Zou SJ
Lasers in medical science · 47 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2012-09-21 · Lasers Med Sci · vol. 28 · número 6 · págs. 1581–1589
- Editorial
- Springer Science+Business Media
- Citado
- 71 citas · más que el 68% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Orthodontics and Dentofacial Orthopedics · Temporomandibular Joint Disorders
- Palabras clave
- low-level laser therapy, orthodontic pain, pain management, pain intensity, pain onset, orthodontic appliances
- MeSH
- humans, pain, pain measurement, treatment outcome, orthodontics, corrective, clinical trials as topic, low-level light therapy
7 autores
- W. L. He🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Chunjie Li🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Z. P. Liu🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- J. F. Sun🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Zehao Hu🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Xing Fu Yin🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Shujuan Zou🇨🇳 · autor de correspondenciaSichuan University; State Key Laboratory of Oral Diseases
Resumen
El texto original del estudio, en el idioma en que se publicó.
This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through CENTRAL, PubMed, Embase, Medline, CNKI, and CBM up to October 2011. Risk of bias assessment was performed via referring to the Cochrane tool for risk of bias assessment. Meta-analysis was implemented using Review Manager 5.1. As a result, four RCTs, two quasi-RCTs, and two CCTs were selected from 152 relevant studies, including 641 patients from six countries. The meta-analysis demonstrated that 24% risk of incidence of pain was reduced by LLLT (RR = 0.76, 95% CI range 0.63-0.92, P = 0.006). In addition, compared to the control group, LLLT brought forward "the most painful day" (MD = -0.42, 95% CI range -0.74- -0.10, P = 0.009). Furthermore, the LLLT group also implied a trend of earlier end of pain compared with the control group (MD = -1.37, 95% CI range -3.37-0.64, P = 0.18) and the pseudo-laser group (MD = -1.04, 95% CI range -4.22-2.15, P = 0.52). However, because of the methodological shortcomings and risk of bias of included trials, LLLT was proved with limited evidence in delaying pain onset and reducing pain intensity. In the future, larger and better-designed RCTs will be required to provide clearer recommendations.
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