Financiado en parte por GlaxoSmithKline
Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance
Rogers PJ, Heatherley SV, Mullings EL, Smith JE
Psychopharmacology · 73 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Empresa
- GlaxoSmithKline
- Gobierno
- Directorate for Biological Sciences
- Gobierno
- Biotechnology and Biological Sciences Research Council
- Subvenciones
- Biotechnology and Biological Sciences Research Council (BBS/B/01855)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2012-10-29 · Psychopharmacology (Berl) · vol. 226 · número 2 · págs. 229–240
- Editorial
- Springer Science+Business Media
- Citado
- 122 citas · más que el 96% de estudios similares · 5.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 42 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · OTHER-OA
- Áreas de investigación
- Coffee research and impacts · Sleep and Work-Related Fatigue · Sleep and related disorders
- Palabras clave
- caffeine, caffeine withdrawal, habitual caffeine consumption, alertness, cognitive performance, sleepiness, reaction time, recognition memory, anxiety, jitteriness, motor performance, caffeine tolerance, placebo
- MeSH
- humans, substance withdrawal syndrome, caffeine, central nervous system stimulants, double-blind method, anxiety, cognition, task performance and analysis, psychomotor performance, reaction time, dose-response relationship, drug, computers, adolescent, adult, middle aged, female, male, young adult
4 autores
- Peter J. Rogers🇬🇧 · autor de correspondenciaUniversity of Bristol
- Susan V. Heatherley🇬🇧University of Bristol
- Emma L. Mullings🇬🇧University of Manchester; University of Bristol
- Jessica E. Smith🇬🇧University of Bristol
Resumen
El texto original del estudio, en el idioma en que se publicó.
Rationale
Despite 100 years of psychopharmacological research, the extent to which caffeine consumption benefits human functioning remains unclear.
Objectives
To measure the effects of overnight caffeine abstinence and caffeine administration as a function of level of habitual caffeine consumption.
Methods
Medium-high (n = 212) and non-low (n = 157) caffeine consumers completed self-report measures and computer-based tasks before (starting at 10:30 AM) and after double-blind treatment with either caffeine (100 mg, then 150 mg) or placebo. The first treatment was given at 11:15 AM and the second at 12:45 PM, with post-treatment measures repeated twice between 1:45 PM and 3:30 PM.
Results
Caffeine withdrawal was associated with some detrimental effects at 10:30 AM, and more severe effects, including greater sleepiness, lower mental alertness, and poorer performance on simple reaction time, choice reaction time and recognition memory tasks, later in the afternoon. Caffeine improved these measures in medium-high consumers but, apart from decreasing sleepiness, had little effect on them in non-low consumers. The failure of caffeine to increase mental alertness and improve mental performance in non-low consumers was related to a substantial caffeine-induced increase in anxiety/jitteriness that offset the benefit of decreased sleepiness. Caffeine enhanced physical performance (faster tapping speed and faster simple and choice reaction times) in both medium-high and non-low consumers.
Conclusions
While caffeine benefits motor performance and tolerance develops to its tendency to increase anxiety/jitteriness, tolerance to its effects on sleepiness means that frequent consumption fails to enhance mental alertness and mental performance.
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