Meat consumption and mortality--results from the European Prospective Investigation into Cancer and Nutrition
Rohrmann S, Overvad K, Bueno-de-Mesquita HB, Jakobsen MU, Egeberg R, Tjønneland A, Nailler L, Boutron-Ruault MC, Clavel-Chapelon F, Krogh V, Palli D, Panico S, Tumino R, Ricceri F, Bergmann MM, Boeing H, Li K, Kaaks R, Khaw KT, Wareham NJ, Crowe FL, Key TJ, Naska A, Trichopoulou A, Trichopoulos D, Leenders M, Peeters PH, Engeset D, Parr CL, Skeie G, Jakszyn P, Sánchez MJ, Huerta JM, Redondo ML, Barricarte A, Amiano P, Drake I, Sonestedt E, Hallmans G, Johansson I, Fedirko V, Romieux I, Ferrari P, Norat T, Vergnaud AC, Riboli E, Linseisen J
BMC medicine · 247 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Deutsches Krebsforschungszentrum
- Organización sin fines de lucro
- Kreftforeningen
- Organización sin fines de lucro
- Wellcome Trust
- Organización sin fines de lucro
- Cancer Research UK
- Gobierno
- National Institute for Health and Care Research
- Organización sin fines de lucro
- British Heart Foundation
- Gobierno
- European Commission
- Gobierno
- Institut National de la Santé et de la Recherche Médicale
- Gobierno
- Bundesministerium für Bildung und Forschung
- Organización sin fines de lucro
- Cancerfonden
- Organización sin fines de lucro
- Ligue Contre le Cancer
- Organización sin fines de lucro
- Stavros Niarchos Foundation
- Gobierno
- NordForsk
- Organización sin fines de lucro
- Associazione Italiana per la Ricerca sul Cancro
- Organización sin fines de lucro
- Deutsche Krebshilfe
- Universidad u hospital
- Institut Gustave-Roussy
- Organización sin fines de lucro
- Mutuelle Générale de l'Education Nationale
- Organización sin fines de lucro
- Hellenic Health Foundation
- Gobierno
- Medical Research Council
- Organización sin fines de lucro
- World Cancer Research Fund
- Gobierno
- Instituto de Salud Carlos III
- Gobierno
- National Institute for Health Research (NIHR)
- Subvenciones
- Instituto de Salud Carlos III (C03/09); Cancer Research UK (14136)
Según 22 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2013-03-07 · BMC Med · vol. 11 · número 1 · pág. 63
- Editorial
- BioMed Central
- Citado
- 453 citas · más que el 100% de estudios similares · 42.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 43 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Agriculture Sustainability and Environmental Impact · Consumer Attitudes and Food Labeling
- Palabras clave
- Medicine, Prospective cohort study, European Prospective Investigation into Cancer and Nutrition, Environmental health, Cancer, Consumption (sociology), Internal medicine
- MeSH
- humans, neoplasms, cardiovascular diseases, diet, nutrition surveys, survival analysis, cohort studies, prospective studies, feeding behavior, meat, adult, aged, middle aged, united states, female, male
47 autores
- Sabine Rohrmann🇨🇭 · autor de correspondenciaUniversity of Zurich; Institute of Social and Preventive Medicine
- Kim Overvad🇩🇰Aarhus University
- H. Bas Bueno-de-Mesquita🇳🇱University Medical Center Utrecht; National Institute for Public Health and the Environment
- Marianne Uhre Jakobsen🇩🇰Aarhus University
- Rikke Egeberg🇩🇰Danish Cancer Society
- Anne Marie Tjønneland🇩🇰Danish Cancer Society
- Laura Nailler🇫🇷Inserm; Institut Gustave Roussy; Centre de recherche en Epidémiologie et Santé des Populations
- Marie‐Christine Boutron‐Ruault🇫🇷Inserm; Institut Gustave Roussy; Centre de recherche en Epidémiologie et Santé des Populations
- Françoise Clavel-Chapelon🇫🇷Inserm; Institut Gustave Roussy; Centre de recherche en Epidémiologie et Santé des Populations
- Vittorio Krogh🇮🇹Fondazione IRCCS Istituto Nazionale dei Tumori
- Domenico Palli🇮🇹Piedmont Reference Center for Epidemiology and Cancer Prevention
- Salvatore Panico🇮🇹Federico II University Hospital
- Rosario Tumino🇮🇹Azienda Usl 8 Arezzo
- Fulvio Ricceri🇮🇹Italian institute for Genomic Medicine
- Manuela M. Bergmann🇩🇪German Institute of Human Nutrition
- Heiner Boeing🇩🇪German Institute of Human Nutrition
- Kuanrong Li🇩🇪German Cancer Research Center; DKFZ-ZMBH Alliance
- Rudolf Kaaks🇩🇪German Cancer Research Center; DKFZ-ZMBH Alliance
- Kay‐Tee Khaw🇬🇧University of Cambridge
- Nicholas J. Wareham🇬🇧MRC Epidemiology Unit; Medical Research Council
- Francesca L. Crowe🇬🇧University of Oxford
- Timothy J. Key🇬🇧University of Oxford
- Androniki Naska🇬🇷National and Kapodistrian University of Athens
- Antonia Trichopoulou🇬🇷National and Kapodistrian University of Athens; Hellenic Health Foundation
- Dimitirios Trichopoulos🇺🇸🇬🇷Harvard University; Academy of Athens; Hellenic Health Foundation
- Max B. Leenders🇳🇱University Medical Center Utrecht
- Petra H. M. Peeters🇳🇱🇬🇧University Medical Center Utrecht; Imperial College London
- Dagrun Engeset🇳🇴UiT The Arctic University of Norway
- Christine Louise Parr🇳🇴University of Oslo
- Guri Skeie🇳🇴UiT The Arctic University of Norway
- Paula Gabriela Jakszyn🇪🇸Institut Català d'Oncologia
- María‐José Sánchez🇪🇸Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública; Andalusian School of Public Health
- José María Huerta🇪🇸Servicio Murciano de Salud; Andalusian School of Public Health; Universidad de Murcia
- María Luisa Redondo
- Aurelio Barricarte🇪🇸Universidad Pública de Navarra (UPNA); Navarre Institute of Health Research; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
- Pilar Amiano🇪🇸Basque Government; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
- Isabel Drake🇸🇪Lund University
- Emily Sonestedt🇸🇪Lund University
- Göran Hallmans🇸🇪Umeå University
- Ingegerd Johansson🇸🇪Umeå University
- Veronika Fedirko🇫🇷Centre international de recherche sur le cancer
- Isabelle Romieux🇫🇷Centre international de recherche sur le cancer
- Pietro Ferrari🇫🇷Centre international de recherche sur le cancer
- Teresa Norat🇬🇧Imperial College London
- Anne Claire Vergnaud🇬🇧Imperial College London
- Elio Ríboli🇬🇧Imperial College London
- Jakob Linseisen🇩🇪German Cancer Research Center; Helmholtz Munich; DKFZ-ZMBH Alliance
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Recently, some US cohorts have shown a moderate association between red and processed meat consumption and mortality supporting the results of previous studies among vegetarians. The aim of this study was to examine the association of red meat, processed meat, and poultry consumption with the risk of early death in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Methods
Included in the analysis were 448,568 men and women without prevalent cancer, stroke, or myocardial infarction, and with complete information on diet, smoking, physical activity and body mass index, who were between 35 and 69 years old at baseline. Cox proportional hazards regression was used to examine the association of meat consumption with all-cause and cause-specific mortality.
Results
As of June 2009, 26,344 deaths were observed. After multivariate adjustment, a high consumption of red meat was related to higher all-cause mortality (hazard ratio (HR) = 1.14, 95% confidence interval (CI) 1.01 to 1.28, 160+ versus 10 to 19.9 g/day), and the association was stronger for processed meat (HR = 1.44, 95% CI 1.24 to 1.66, 160+ versus 10 to 19.9 g/day). After correction for measurement error, higher all-cause mortality remained significant only for processed meat (HR = 1.18, 95% CI 1.11 to 1.25, per 50 g/d). We estimated that 3.3% (95% CI 1.5% to 5.0%) of deaths could be prevented if all participants had a processed meat consumption of less than 20 g/day. Significant associations with processed meat intake were observed for cardiovascular diseases, cancer, and 'other causes of death'. The consumption of poultry was not related to all-cause mortality.
Conclusions
The results of our analysis support a moderate positive association between processed meat consumption and mortality, in particular due to cardiovascular diseases, but also to cancer.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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