Does magnesium supplementation improve body composition and muscle strength in middle-aged overweight women? A double-blind, placebo-controlled, randomized clinical trial
Moslehi N, Vafa M, Sarrafzadeh J, Rahimi-Foroushani A
Biological trace element research · 34 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Tehran University of Medical Sciences and Health Services
Según 1 financiador declarado.
Publicación
- Publicado
- 2013-04-26 · Biol Trace Elem Res · vol. 153 · número 1-3 · págs. 111–118
- Editorial
- Springer Science+Business Media
- Citado
- 42 citas · más que el 77% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 47 trabajos
- Acceso
- De pago
- Áreas de investigación
- Magnesium in Health and Disease · Nutrition and Health in Aging · Nutrition and Health Studies
- Palabras clave
- magnesium supplementation, magnesium oxide, body composition, muscle strength, overweight women, middle-aged women, lean body mass, fat mass, grip strength, quadriceps strength, functional mobility, serum magnesium, dietary intervention
- MeSH
- humans, magnesium, placebos, double-blind method, body composition, dietary supplements, adult, middle aged, female, overweight, muscle strength
4 autores
- Nazanin Moslehi🇮🇷Tehran University of Medical Sciences
- Mohammadreza Vafa🇮🇷 · autor de correspondenciaFiroozgar General Hospital; Tehran University of Medical Sciences
- Javad Sarrafzadeh🇮🇷Tehran University of Medical Sciences
- Abbas Rahimiforoushani🇮🇷Tehran University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Muscle strength, an independent predictor of metabolic disorders, disability, and mortality, reduces gradually with advancing age. Little is known about the influence of nutritional intervention on muscle strength in middle-aged. The aim of the present study is to examine whether magnesium could improve body composition and muscle strength in middle-aged overweight women. In this double-blinded, placebo-controlled, randomized trial, a total of 74 healthy middle-aged overweight women (25 ≤ BMI ≤ 30 kg/m(2)) received either 250 mg magnesium in the form of magnesium oxide or placebo daily for 8 weeks. Body composition was assessed using Bioelectrical Impedance Analysis (BIA). Handgrip strength and knee extension strength were measured with isometric dynamometry. Functional mobility was assessed using Time Get Up and Go Test (TGUG). A significant increase in mean lean body mass was observed (P = 0.05) accompanied with a significant decrease in fat mass (P = 0.02) solely in the magnesium group at the end of 8 weeks compared to baseline values but the changes did not reach significant as compared to placebo group. Handgrip strength and TGUG improved in the magnesium group compared to baseline but they were not significant compared to placebo. There were no significant differences in increasing knee extension strength in the magnesium group as compared with placebo. Baseline values of serum magnesium and muscle strength of participants did not indicate any influences on response to magnesium supplementation. Our findings indicate that magnesium as magnesium oxide, 250 mg/day, for 8 weeks do not lead to a significant greater gain in muscle strength and function compared to placebo.
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