Egg consumption in relation to risk of cardiovascular disease and diabetes: a systematic review and meta-analysis
Shin JY, Xun P, Nakamura Y, He K
The American journal of clinical nutrition · 189 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute of Diabetes and Digestive and Kidney Diseases
- Gobierno
- National Institute of Neurological Disorders and Stroke
- Gobierno
- NIDDK NIH HHS
- Gobierno
- NINDS NIH HHS
- Subvenciones
- National Institute of Diabetes and Digestive and Kidney Diseases (R21 DK073812); National Institute of Neurological Disorders and Stroke (R21NS056445)
Según 5 financiadores declarados.
Publicación
- Publicado
- 2013-05-16 · Am J Clin Nutr · vol. 98 · número 1 · págs. 146–159
- Editorial
- Elsevier BV
- Citado
- 290 citas · más que el 96% de estudios similares · 4.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 81 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nutritional Studies and Diet · Cardiovascular Health and Risk Factors · Nuts composition and effects
- Palabras clave
- egg consumption, cardiovascular disease, type 2 diabetes, ischemic heart disease, stroke, cardiac mortality, diabetes comorbidity, dietary cholesterol, dietary fat
- MeSH
- humans, cardiovascular diseases, diabetes mellitus, type 2, incidence, risk factors, eggs, databases, factual, randomized controlled trials as topic
4 autores
- Jang Yel Shin🇺🇸🇰🇷🇯🇵University of North Carolina at Chapel Hill; Yonsei University; Kyoto Women's University; Indiana University Bloomington; Indiana University
- Pengcheng Xun🇺🇸🇰🇷🇯🇵University of North Carolina at Chapel Hill; Yonsei University; Kyoto Women's University; Indiana University Bloomington; Indiana University
- Yasuyuki Nakamura🇺🇸🇰🇷🇯🇵University of North Carolina at Chapel Hill; Yonsei University; Kyoto Women's University; Indiana University Bloomington; Indiana University
- Ka He🇺🇸🇰🇷🇯🇵 · autor de correspondenciaUniversity of North Carolina at Chapel Hill; Yonsei University; Kyoto Women's University; Indiana University Bloomington; Indiana University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The associations of egg consumption with cardiovascular disease (CVD) and diabetes are still unclear.
Objective
We aimed to quantitatively summarize the literature on egg consumption and risk of CVD, cardiac mortality, and type 2 diabetes by conducting a meta-analysis of prospective cohort studies.
Design
A systematic literature review was conducted for published studies in PubMed and EMBASE through March 2012. Additional information was retrieved through Google or a hand review of the reference from relevant articles. Studies were included if they had a prospective study design, were published in English-language journals, and provided HRs and 95% CIs for the associations of interest. Data were independently extracted by 2 investigators, and the weighted HRs and 95% CIs for the associations of interest were estimated by using a random-effects model.
Results
A total of 22 independent cohorts from 16 studies were identified, including participants ranging in number from 1600 to 90,735 and in follow-up time from 5.8 to 20.0 y. Comparison of the highest category (≥1 egg/d) of egg consumption with the lowest (<1 egg/wk or never) resulted in a pooled HR (95% CI) of 0.96 (0.88, 1.05) for overall CVD, 0.97 (0.86, 1.09) for ischemic heart disease, 0.93 (0.81, 1.07) for stroke, 0.98 (0.77, 1.24) for ischemic heart disease mortality, 0.92 (0.56, 1.50) for stroke mortality, and 1.42 (1.09, 1.86) for type 2 diabetes. Of the studies conducted in diabetic patients, the pooled HR (95% CI) was 1.69 (1.09, 2.62) for overall CVD.
Conclusions
This meta-analysis suggests that egg consumption is not associated with the risk of CVD and cardiac mortality in the general population. However, egg consumption may be associated with an increased incidence of type 2 diabetes among the general population and CVD comorbidity among diabetic patients.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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