Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (IRAS)
Lee CT, Liese AD, Lorenzo C, Wagenknecht LE, Haffner SM, Rewers MJ, Hanley AJ
Public health nutrition · 7 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of Toronto
- Gobierno
- National Institutes of Health
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Institute of Diabetes and Digestive and Kidney Diseases
- Gobierno
- NIDDK NIH HHS
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (U01 HL 47892); National Heart, Lung, and Blood Institute (HL-47902); National Heart, Lung, and Blood Institute (R01-58329); National Heart, Lung, and Blood Institute (U01 HL 47902); National Institutes of Health (M01-RR-43); National Heart, Lung, and Blood Institute (HL 47892); National Heart, Lung, and Blood Institute (U01 HL047892); National Institute of Diabetes and Digestive and Kidney Diseases (R01 DK029867); National Heart, Lung, and Blood Institute (DK-29867); National Heart, Lung, and Blood Institute (U01 HL047902); National Institutes of Health (DK29867)
Según 6 financiadores declarados.
Publicación
- Publicado
- 2013-06-19 · Public Health Nutr · vol. 17 · número 7 · págs. 1595–1602
- Editorial
- Cambridge University Press
- Citado
- 11 citas · más que el 68% de estudios similares · 0.3× el promedio de su campo
- Referencias
- 24 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Consumer Attitudes and Food Labeling
- Palabras clave
- Insulin resistance, Insulin, Internal medicine, Endocrinology, Medicine, Insulin sensitivity, Diabetes mellitus, Cholesterol
- MeSH
- humans, insulin resistance, insulin, blood glucose, cholesterol, dietary, glucose tolerance test, body mass index, diet, fasting, cross-sectional studies, feeding behavior, eggs, middle aged, female, male
7 autores
- Chee-Tin Christine Lee🇨🇦University of Toronto
- Angela D. Liese🇺🇸University of South Carolina
- Carlos Lorenzo🇺🇸The University of Texas at San Antonio Health Science Center
- Lynne E. Wagenknecht🇺🇸Wake Forest University
- Steven M. Haffner🇺🇸Baylor College of Medicine
- Marian Rewers🇺🇸University of Colorado Denver
- Anthony J. Hanley🇨🇦 · autor de correspondenciaMount Sinai Hospital; University of Toronto; Public Health Ontario
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
To examine the association between egg consumption and measures of insulin sensitivity (SI), acute insulin response (AIR) and metabolic clearance rate of insulin (MCRI).
Design
Cross-sectional analysis.
Settings
Egg consumption, categorized as <1/week, 1 to <3/week, 3 to <5/week and ≥5/week, was measured using a validated FFQ. SI, AIR and MCRI were determined from frequently sampled intravenous glucose tolerance tests.
Subjects
Non-diabetic participants (n 949) in the Insulin Resistance Atherosclerosis Study (IRAS).
Results
Egg consumption was inversely associated with SI and MCRI, and positively associated with fasting insulin in regression models adjusted for demographic, socio-economic, lifestyle and dietary factors (β = -0·22, 95 % CI -0·38, -0·045, P = 0·05 for SI; β = -0·20, 95 % CI -0·34, -0·055, P = 0·005 for MCRI; β = 0·35, 95 % CI 0·15, 0·54, P = 0·002 for fasting insulin; all P values for linear trend). These associations remained significant after additionally adjusting for energy intake or dietary saturated fat, although dietary cholesterol and BMI attenuated these associations to non-significance. Egg consumption was not associated with AIR.
Conclusions
Dietary cholesterol and BMI appear to mediate the inverse association of egg consumption with insulin sensitivity and clearance. Alternatively, egg consumption may be clustered with other dietary behaviours which increase BMI, hence negatively impacting on insulin sensitivity and clearance.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.