Effects of exercise with or without blueberries in the diet on cardio-metabolic risk factors: an exploratory pilot study in healthy subjects
Nyberg S, Gerring E, Gjellan S, Vergara M, Lindström T, Nystrom FH
Upsala journal of medical sciences · 22 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Linköpings Universitet
Según 1 financiador declarado.
Publicación
- Publicado
- 2013-08-27 · Ups J Med Sci · vol. 118 · número 4 · págs. 247–255
- Editorial
- Taylor & Francis
- Citado
- 30 citas · más que el 80% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY
- Áreas de investigación
- Exercise and Physiological Responses · Cardiovascular and exercise physiology · Physical Activity and Health
- Palabras clave
- blueberry, physical activity, cardiometabolic risk factors, insulin sensitivity, fasting blood glucose, HDL cholesterol, triglycerides, antioxidants, running, dietary supplementation, healthy adults
- MeSH
- humans, cardiovascular diseases, insulin, blood glucose, triglycerides, troponin t, antioxidants, exercise, diet, risk factors, pilot projects, cross-over studies, adult, middle aged, female, male, cholesterol, ldl, cholesterol, hdl, young adult, healthy volunteers, blueberry plants
6 autores
- Sofia Nyberg🇸🇪Linköping University
- Edvard Gerring🇸🇪Linköping University
- Solveig Gjellan🇸🇪Linköping University
- Marta Vergara🇸🇪Linköping University
- Torbjörn Lindström🇸🇪Linköping University
- Fredrik Hans Nyström🇸🇪Linköping University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The improvement of insulin sensitivity by exercise has been shown to be inhibited by supplementation of vitamins acting as antioxidants.
Objective
To examine effects of exercise with or without blueberries, containing natural antioxidants, on cardio-metabolic risk factors.
Methods
Fifteen healthy men and 17 women, 27.6 ± 6.5 years old, were recruited, and 26 completed a randomized cross-over trial with 4 weeks of exercise by running/jogging 5 km five times/week and 4 weeks of minimal physical activity. Participants were also randomized to consume 150 g of blueberries, or not, on exercise days. Laboratory variables were measured before and after a 5 km running-race at maximal speed at the beginning and end of each period, i.e. there were four maximal running-races and eight samplings in total for each participant.
Results
Insulin and triglyceride levels were reduced while HDL-cholesterol increased by exercise compared with minimal physical activity. Participants randomized to consume blueberries showed an increase in fasting glucose levels compared with controls, during the exercise period (blueberries: from 5.12 ± 0.49 mmol/l to 5.32 ± 0.29 mmol/l; controls: from 5.24 ± 0.27 mmol/l to 5.17 ± 0.23 mmol/l, P = 0.04 for difference in change). Triglyceride levels fell in the control group (from 1.1 ± 0.49 mmol/l to 0.93 ± 0.31 mmol/l, P = 0.02), while HDL-cholesterol increased in the blueberry group (from 1.51 ± 0.29 mmol/l to 1.64 ± 0.33 mmol/l, P = 0.006).
Conclusions
Ingestion of blueberries induced differential effects on cardio-metabolic risk factors, including increased levels of both fasting glucose and HDL-cholesterol. However, since it is possible that indirect effects on food intake were induced, other than consumption of blueberries, further studies are needed to confirm the findings.
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