Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies
Jiang X, Zhang D, Jiang W
European journal of nutrition · 144 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2013-10-22 · Eur J Nutr · vol. 53 · número 1 · págs. 25–38
- Editorial
- Springer Science+Business Media
- Citado
- 195 citas · más que el 91% de estudios similares · 3.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 59 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Nutritional Studies and Diet · Metabolism, Diabetes, and Cancer
- Palabras clave
- coffee consumption, caffeine consumption, decaffeinated coffee, type 2 diabetes, diabetes incidence, dose-response relationship, sex differences, smoking status, body mass index
- MeSH
- humans, diabetes mellitus, type 2, caffeine, body mass index, incidence, risk factors, dose-response relationship, drug, coffee, female, male, randomized controlled trials as topic
3 autores
- Xiubo Jiang🇨🇳Qingdao University
- Dongfeng Zhang🇨🇳 · autor de correspondenciaQingdao University
- Wenjie Jiang🇨🇳Qingdao University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Coffee and caffeine have been linked to type 2 diabetes mellitus (T2DM). A dose-response meta-analysis of prospective studies was conducted to assess the association between coffee and caffeine intake and T2DM incidence.
Methods
Pertinent studies were identified by a search of PubMed and EMBASE. The fixed- or random-effect pooled measure was selected based on between-study heterogeneity. Dose-response relationship was assessed by restricted cubic spline.
Results
Compared with the lowest level, the pooled relative risk (95 % CI) of T2DM was 0.71 (0.67-0.76) for the highest level of coffee intake (26 articles involving 50,595 T2DM cases and 1,096,647 participants), 0.79 (0.69-0.91) for the highest level of decaffeinated coffee intake (10 articles involving 29,165 T2DM cases and 491,485 participants) and 0.70 (0.65-0.75) for the highest level of caffeine intake (6 articles involving 9,302 T2DM cases and 321,960 participants). The association of coffee, decaffeinated coffee and caffeine intake with T2DM incidence was stronger for women than that for men. A stronger association of coffee intake with T2DM incidence was found for non-smokers and subjects with body mass index <25 kg/m(2). Dose-response analysis suggested that incidence of T2DM decreased by 12 % [0.88 (0.86-0.90)] for every 2 cups/day increment in coffee intake, 11 % [0.89 (0.82-0.98)] for every 2 cups/day increment in decaffeinated coffee intake and 14 % [0.86 (0.82-0.91)] for every 200 mg/day increment in caffeine intake.
Conclusions
Coffee and caffeine intake might significantly reduce the incidence of T2DM.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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