Creatine supplementation post-exercise does not enhance training-induced adaptations in middle to older aged males
Cooke MB, Brabham B, Buford TW, Shelmadine BD, McPheeters M, Hudson GM, Stathis C, Greenwood M, Kreider R, Willoughby DS
European journal of applied physiology · 27 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Baylor University
- Gobierno
- National Institute on Aging
- Gobierno
- NIA NIH HHS
- Subvenciones
- National Institute on Aging (P30AG028740)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2014-03-16 · Eur J Appl Physiol · vol. 114 · número 6 · págs. 1321–1332
- Editorial
- Springer Science+Business Media
- Citado
- 58 citas · más que el 70% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 44 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Nutrition and Health in Aging
- Palabras clave
- creatine monohydrate, post-exercise supplementation, resistance training, older adults, middle-aged men, body composition, muscle strength, fat-free mass, myofibrillar proteins, muscle fiber cross-sectional area, muscle hypertrophy, training effects
- MeSH
- muscle, skeletal, humans, creatine, double-blind method, adaptation, physiological, dietary supplements, aged, middle aged, male, muscle strength, resistance training
10 autores
- Matthew B. Cooke🇺🇸🇦🇺 · autor de correspondenciaBaylor University; Victoria University
- Brian Brabham🇺🇸University of Mary Hardin–Baylor
- Thomas W. Buford🇺🇸University of Florida
- Brian Shelmadine🇺🇸Baylor University
- Matthew J. McPheeters🇺🇸Baylor University
- Geoffrey M. Hudson🇺🇸George Washington University
- Christos G. Stathis🇦🇺Victoria University
- Mike Greenwood🇺🇸Texas A&M University
- Richard B. Kreider🇺🇸Texas A&M University
- Darryn S. Willoughby🇺🇸Baylor University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
The present study evaluated the effects of creatine monohydrate (CrM) consumption post-exercise on body composition and muscle strength in middle to older males following a 12-week resistance training program.
Methods
In a double-blind, randomized trial, 20 males aged between 55 and 70 years were randomly assigned to consume either CrM-carbohydrate (CHO) [20 g days(-1) CrM + 5 g days(-1) CHO × 7 days, then 0.1 g kg(-1) CrM + 5 g CHO on training days (average dosage of ~8.8 g)] or placebo CHO (20 g days(-1) CHO × 7 days, then 5 g CHO on training days) while participating in a high intensity resistance training program [3 sets × 10 repetitions at 75% of 1 repetition maximum (1RM)], 3 days weeks(-1) for 12 weeks. Following the initial 7-day "loading" phase, participants were instructed to ingest their supplement within 60 min post-exercise. Body composition and muscle strength measurements, blood collection and vastus lateralis muscle biopsy were completed at 0, 4, 8 and 12 weeks of the supplement and resistance training program.
Results
A significant time effect was observed for 1RM bench press (p = 0.016), leg press (p = 0.012), body mass (p = 0.03), fat-free mass (p = 0.005) and total myofibrillar protein (p = 0.005). A trend for larger muscle fiber cross-sectional area in the type II fibers compared to type I fibers was observed following the 12-week resistance training (p = 0.08). No supplement interaction effects were observed.
Conclusion
Post-exercise ingestion of creatine monohydrate does not provide greater enhancement of body composition and muscle strength compared to resistance training alone in middle to older males.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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