Financiado en parte por Almond Board of California
Effects of almond and pistachio consumption on gut microbiota composition in a randomised cross-over human feeding study
Ukhanova M, Wang X, Baer DJ, Novotny JA, Fredborg M, Mai V
The British journal of nutrition · 115 citas
Etiquetas de revisión
Alimentación controladaFinanciado por la industriaSolo mecanismosDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Solo mecanismos
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Almond Board of California
Según 1 financiador declarado.
Publicación
- Publicado
- 2014-03-18 · Br J Nutr · vol. 111 · número 12 · págs. 2146–2152
- Editorial
- Cambridge University Press
- Citado
- 153 citas · más que el 97% de estudios similares · 6.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 28 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Diet and metabolism studies
- Palabras clave
- Food science, Gut flora, Composition (language), Biology, Biochemistry
- MeSH
- gastrointestinal tract, intestines, intestinal mucosa, feces, humans, gram-negative bacteria, gram-positive bacteria, bifidobacterium, fungi, pistacia, prunus, nuts, mycological typing techniques, cross-over studies, principal component analysis, maryland, functional food, lactobacillales, prebiotics, molecular typing
6 autores
- Maria Ukhanova🇺🇸University of Florida
- Xiaoyu Wang🇺🇸University of Florida
- David J. Baer🇺🇸Agricultural Research Service; Beltsville Human Nutrition Research Center
- Janet A. Novotny🇺🇸Agricultural Research Service; Beltsville Human Nutrition Research Center
- Marlene Fredborg🇩🇰🇺🇸Aarhus University; University of Florida
- Volker Mai🇺🇸 · autor de correspondenciaUniversity of Florida
Resumen
El texto original del estudio, en el idioma en que se publicó.
The modification of microbiota composition to a 'beneficial' one is a promising approach for improving intestinal as well as overall health. Natural fibres and phytochemicals that reach the proximal colon, such as those present in various nuts, provide substrates for the maintenance of healthy and diverse microbiota. The effects of increased consumption of specific nuts, which are rich in fibre as well as various phytonutrients, on human gut microbiota composition have not been investigated to date. The objective of the present study was to determine the effects of almond and pistachio consumption on human gut microbiota composition. We characterised microbiota in faecal samples collected from volunteers in two separate randomised, controlled, cross-over feeding studies (n 18 for the almond feeding study and n 16 for the pistachio feeding study) with 0, 1·5 or 3 servings/d of the respective nuts for 18 d. Gut microbiota composition was analysed using a 16S rRNA-based approach for bacteria and an internal transcribed spacer region sequencing approach for fungi. The 16S rRNA sequence analysis of 528 028 sequence reads, retained after removing low-quality and short-length reads, revealed various operational taxonomic units that appeared to be affected by nut consumption. The effect of pistachio consumption on gut microbiota composition was much stronger than that of almond consumption and included an increase in the number of potentially beneficial butyrate-producing bacteria. Although the numbers of bifidobacteria were not affected by the consumption of either nut, pistachio consumption appeared to decrease the number of lactic acid bacteria (P< 0·05). Increasing the consumption of almonds or pistachios appears to be an effective means of modifying gut microbiota composition.
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