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Estudio de casos y controles2014

Photobiomodulation in the treatment of patients with non-center-involving diabetic macular oedema

Tang J, Herda AA, Kern TS

The British journal of ophthalmology · 57 citas

Cómo se estudió

Diseño
Estudio de casos y controles (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Eye Institute
Gobierno
NEI NIH HHS
Subvenciones
National Eye Institute (R01EY022938); National Eye Institute (R01 EY000300); National Eye Institute (R01EY00300)

Según 2 financiadores declarados.

Publicación

Publicado
2014-03-28 · Br J Ophthalmol · vol. 98 · número 8 · págs. 1013–1015
Editorial
BMJ
Citado
77 citas · más que el 95% de estudios similares · 4.6× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
8 trabajos
Acceso
Acceso abierto (copia en repositorio)
Áreas de investigación
Laser Applications in Dentistry and Medicine · Retinal Diseases and Treatments · Dermatologic Treatments and Research
Palabras clave
Medicine, Diabetic retinopathy, Diabetes mellitus, Visual acuity, Adverse effect, Ophthalmology, Retinal, Retinopathy, Surgery, Internal medicine
MeSH
humans, diabetic retinopathy, phototherapy, case-control studies, adult, aged, middle aged, point-of-care systems, male, macular edema

3 autores

  • Johnny Cheuk On Tang🇺🇸 · autor de correspondenciaLouis Stokes Cleveland VA Medical Center
  • Ashley A. Herda🇺🇸University of Kansas Medical Center
  • Timothy S. Kern🇺🇸Louis Stokes Cleveland VA Medical Center; University School; Case Western Reserve University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Purpose

Far-red/near-infrared phototherapy or photobiomodulation (PBM) has recently been reported to be an effective and non-invasive treatment method to inhibit lesions of diabetic retinopathy (DR) in animals. This study investigated the safety and efficacy of PBM in diabetic patients to treat non-center-involving diabetic macular oedema (NCDME).

Methods

This was a non-randomised, consecutive, case series, where 4 patients with type 2 diabetes with NCDME were treated for 160 s per day with PBM for 2-9 months. Demographic data including age, sex, HbA1c%, electronic ETDRS visual acuity, and retinal and macular thickness were measured using spectral domain ocular coherence tomography (SD-OCT) before and after treatment.

Results

Four eyes of 4 patients were treated, with fellow eyes serving as untreated controls. Daily PBM treatment for only 80 s per treatment twice daily caused a significant reduction in focal retinal thickening in all 4 treated eyes. No adverse effects attributable to therapy were noted by the patients or study investigators during the study period.

Conclusions

PBM potentially offers a non-invasive and cost-effective therapeutic option for patients with NCDME. Further studies of this therapeutic option in DR are warranted.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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