Nut consumption in relation to cardiovascular disease risk and type 2 diabetes: a systematic review and meta-analysis of prospective studies
Zhou D, Yu H, He F, Reilly KH, Zhang J, Li S, Zhang T, Wang B, Ding Y, Xi B
The American journal of clinical nutrition · 96 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Universidad u hospital
- Guangdong Medical College
- Gobierno
- National Institutes of Health
- Universidad u hospital
- Science and Technology Innovation Team Project in Doctor Granting of Guangdong Medical College
- Gobierno
- Key Projects of Science and Technology Plan Medical and Scientific Research Units of Dongguan
- Gobierno
- Science and Technology Innovation Project of Guangdong Province
- Universidad u hospital
- Key Disciplines of Guangdong Medical College Project
- Gobierno
- NIH
- Subvenciones
- National Natural Science Foundation of China (81273166); National Institutes of Health (psychoceramics-1152342)
Según 8 financiadores declarados.
Publicación
- Publicado
- 2014-05-08 · Am J Clin Nutr · vol. 100 · número 1 · págs. 270–277
- Editorial
- Elsevier BV
- Citado
- 138 citas · más que el 88% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 44 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Cardiovascular Health and Risk Factors
- Palabras clave
- nut consumption, cardiovascular risk, coronary artery disease, stroke, hypertension, type 2 diabetes, dietary fat, prospective cohort
- MeSH
- humans, nuts, cardiovascular diseases, diabetes mellitus, type 2, diet, risk factors, risk reduction behavior, databases, factual
10 autores
- Donghao Zhou🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Haibing Yu🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Fang He🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Kathleen H. Reilly🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Jingling Zhang🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Shuangshuang Li🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Tao Zhang🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Baozhen Wang🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Yuanlin Ding🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
- Bo Xi🇨🇳Shandong University; Guangdong Medical College; Linyi People's Hospital; Southern Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Many prospective cohort studies have investigated the association between nut consumption and risk of coronary artery disease (CAD), stroke, hypertension, and type 2 diabetes (T2D). However, results have been inconsistent.
Objective
We aimed to investigate the association between nut consumption and risk of CAD, stroke, hypertension, and T2D.
Design
PubMed and EMBASE databases were searched up to October 2013. All prospective cohort studies of nut consumption and risk of CAD, stroke, hypertension, and T2D were included. Summary RRs with 95% CIs were estimated by using a fixed- or random-effects model.
Results
A total of 23 prospective studies (9 studies for CAD, 4 studies for stroke, 4 studies for hypertension, and 6 studies for T2D) from 19 publications were included in the meta-analysis. There were 179,885 participants and 7236 CAD cases, 182,730 participants and 5669 stroke cases, 40,102 participants and 12,814 hypertension cases, and 342,213 participants and 14,400 T2D cases. The consumption of each 1 serving of nuts/d was significantly associated with incident CAD (RR: 0.81; 95% CI: 0.72, 0.91; P < 0.001) and hypertension (RR: 0.66; 95% CI: 0.44, 1.00; P = 0.049). However, there was no association between the consumption of each 1 serving of nuts/d and risk of stroke (RR: 0.90; 95% CI: 0.71, 1.14) or T2D (RR: 0.80; 95% CI: 0.57, 1.14).
Conclusions
A higher consumption of nuts was associated with reduced risk of CAD and hypertension but not stroke or T2D. Large randomized controlled trials are warranted to confirm the observed associations.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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