Dietary magnesium intake and risk of cancer: a meta-analysis of epidemiologic studies
Ko HJ, Youn CH, Kim HM, Cho YJ, Lee GH, Lee WK
Nutrition and cancer · 29 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-06-09 · Nutr Cancer · vol. 66 · número 6 · págs. 915–923
- Editorial
- Routledge
- Citado
- 50 citas · más que el 40% de estudios similares · 0.2× el promedio de su campo
- Referencias
- 50 trabajos
- Acceso
- De pago
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments
- Palabras clave
- Meta-analysis, Medicine, Environmental health, Magnesium, Cancer, Internal medicine, Chemistry
- MeSH
- humans, colorectal neoplasms, magnesium, diet, risk factors, observational studies as topic
6 autores
- Hae‐Jin Ko🇰🇷Kyungpook National University
- Chang Ho Youn🇰🇷 · autor de correspondenciaKyungpook National University
- Hyo Min Kim🇰🇷Kyungpook National University Medical Center
- Yoon Jeong Cho🇰🇷Daegu Catholic University
- Geon Ho Lee🇰🇷Daegu Catholic University
- Won Kee Lee🇰🇷Kyungpook National University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The aim of this study was to investigate the association between dietary magnesium and the risk of overall cancer using a meta-analysis. We searched PubMed, SCOPUS, and the Cochrane Review through November 2012. All the articles searched were independently reviewed by 3 authors based on predetermined selection criterion. A total of 13 epidemiologic studies, 6 case-control studies, and 7 prospective cohort studies involving 1,236,004 participants were included in the final analysis. When all studies were pooled, the relative risk (RR) of overall cancer for the highest level of dietary magnesium intake was 0.801 [95% confidence interval (CI): 0.664-0.966) compared with the lowest level of dietary magnesium intake. In subgroup meta-analyses by study design, there was a significant inverse association between dietary magnesium and the risk of cancer in case-control studies (RR = 0.663, 95% CI: 0.475-0.925), whereas there was no significant association in prospective cohort studies (RR = 0.888, 95% CI: 0.745-1.060). Furthermore, there was a significant preventive effect of dietary magnesium for colorectal cancer (RR = 0.775, 95% CI: 0.655-0.919), but not for other cancer. Our meta-analysis showed that higher dietary magnesium intake seems to have a protective effect for cancer, especially colorectal cancer and in females.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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