Ingesting a preworkout supplement containing caffeine, creatine, β-alanine, amino acids, and B vitamins for 28 days is both safe and efficacious in recreationally active men
Kendall KL, Kendall KL, Moon JR, Fairman CM, Spradley BD, Tai CY, Falcone PH, Carson LR, Mosman MM, Joy JM, Kim MP, Serrano ER, Esposito EN
Nutrition research (New York, N.Y.) · 22 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-04-13 · Nutr Res · vol. 34 · número 5 · págs. 442–449
- Editorial
- Elsevier BV
- Citado
- 39 citas · más que el 79% de estudios similares · 1.5× el promedio de su campo
- Referencias
- 59 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Biochemical effects in animals · Coffee research and impacts
- Palabras clave
- caffeine, creatine, beta-alanine, amino acids, B vitamins, supplement safety, body composition, cardiorespiratory fitness, muscle strength, muscular endurance, resting heart rate, blood pressure, renal function, liver function, recreational athletes, men, exercise performance, body fat percentage, fat-free mass, blood urea nitrogen, aspartate aminotransferase
- MeSH
- humans, creatine, caffeine, transaminases, vitamin b complex, amino acids, beta-alanine, blood urea nitrogen, treatment outcome, exercise, double-blind method, body composition, oxygen consumption, blood pressure, heart rate, physical endurance, recreation, dietary supplements, adolescent, male, muscle strength, young adult
12 autores
- Kristina L. Kendall🇺🇸 · autor de correspondenciaGeorgia Southern University
- Jordan Robert Moon🇺🇸United States Sports Academy; MusclePharm Sports Science Institute (United States)
- Ciaran M. Fairman🇺🇸Georgia Southern University
- Brandon D. Spradley🇺🇸United States Sports Academy
- Chih-Yin Tai🇺🇸United States Sports Academy; MusclePharm Sports Science Institute (United States)
- Paul H. Falcone🇺🇸MusclePharm Sports Science Institute (United States)
- Laura R. Carson🇺🇸MusclePharm Sports Science Institute (United States)
- Matt M. Mosman🇺🇸MusclePharm Sports Science Institute (United States)
- Jordan M. Joy🇺🇸MusclePharm Sports Science Institute (United States)
- Michael P. Kim🇺🇸MusclePharm Sports Science Institute (United States)
- Eric R. Serrano🇺🇸MusclePharm Sports Science Institute (United States)
- Enrico N. Esposito🇺🇸University of Mobile; United States Sports Academy
Resumen
El texto original del estudio, en el idioma en que se publicó.
The purpose of this study was to determine the safety and efficacy of consuming a preworkout supplement (SUP) containing caffeine, creatine, β-alanine, amino acids, and B vitamins for 28 days. We hypothesized that little to no changes in kidney and liver clinical blood markers or resting heart rate and blood pressure (BP) would be observed. In addition, we hypothesized that body composition and performance would improve in recreationally active males after 28 days of supplementation. In a double-blind, placebo-controlled study, participants were randomly assigned to ingest one scoop of either the SUP or placebo every day for 28 days, either 20 minutes before exercise or ad libitum on nonexercise days. Resting heart rate and BP, body composition, and fasting blood samples were collected before and after supplementation. Aerobic capacity as well as muscular strength and endurance were also measured. Significant (P < .05) main effects for time were observed for resting heart rate (presupplementation, 67.59 ± 7.90 beats per minute; postsupplementation, 66.18 ± 7.63 beats per minute), systolic BP (presupplementation, 122.41 ± 11.25 mm Hg; postsupplementation, 118.35 ± 11.58 mm Hg), blood urea nitrogen (presupplementation, 13.12 ± 2.55 mg/dL; postsupplementation, 15.24 ± 4.47 mg/dL), aspartate aminotransferase (presupplementation, 34.29 ± 16.48 IU/L; postsupplementation, 24.76 ± 4.71 IU/L), and alanine aminotransferase (presupplementation, 32.76 ± 19.72 IU/L; postsupplementation, 24.88 ± 9.68 IU/L). Significant main effects for time were observed for body fat percentage (presupplementation, 15.55% ± 5.79%; postsupplementation, 14.21% ± 5.38%; P = .004) and fat-free mass (presupplementation, 70.80 ± 9.21 kg; postsupplementation, 71.98 ± 9.27 kg; P = .006). A significant decrease in maximal oxygen consumption (presupplementation, 47.28 ± 2.69 mL/kg per minute; postsupplementation, 45.60 ± 2.81 mL/kg per minute) and a significant increase in percentage of oxygen consumption per unit time at which ventilatory threshold occurred (presupplementation, 64.38% ± 6.63%; postsupplementation, 70.63% ± 6.39%) and leg press one-repetition maximum (presupplementation, 218.75 ± 38.43 kg; postsupplementation, 228.75 ± 44.79 kg) were observed in the SUP only. No adverse effects were noted for renal and hepatic clinical blood markers, resting heart rate, or BP. Supplements containing similar ingredients and doses should be safe for ingestion periods lasting up to 28 days in healthy, recreationally trained, college-aged men.
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