Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis
Dibaba DT, Xun P, Fly AD, Yokota K, He K
Diabetic medicine : a journal of the British Diabetic Association · 57 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Institutes of Health
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Institute of Environmental Health Sciences
- Gobierno
- National Center for Advancing Translational Sciences
- Gobierno
- NHLBI NIH HHS
- Gobierno
- NIEHS NIH HHS
- Gobierno
- NCATS NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (R01 HL081572); National Institute of Environmental Health Sciences (R01ES021735); National Center for Advancing Translational Sciences (UL1TR-001108); National Institutes of Health (R01ES021735); National Institutes of Health (R01HL081572)
Según 7 financiadores declarados.
Publicación
- Publicado
- 2014-06-26 · Diabet Med · vol. 31 · número 11 · págs. 1301–1309
- Editorial
- Wiley
- Citado
- 89 citas · más que el 92% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 51 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Magnesium Alloys: Properties and Applications
- Palabras clave
- Medicine, Metabolic syndrome, Odds ratio, Meta-analysis, Internal medicine, Placebo, Randomized controlled trial, Cohort study, Magnesium deficiency (plants), Relative risk, Magnesium, Confidence interval, Endocrinology, Obesity, Pathology
- MeSH
- humans, magnesium deficiency, magnesium, diet, prevalence, risk factors, cross-sectional studies, evidence-based medicine, metabolic syndrome
5 autores
- Daniel Tefera Dibaba🇺🇸Indiana University Bloomington
- Pengcheng Xun🇺🇸Indiana University Bloomington
- Alyce D. Fly🇺🇸Indiana University Bloomington
- Kaito Yokota🇯🇵Jikei University School of Medicine
- Ka He🇺🇸 · autor de correspondenciaIndiana University Bloomington
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aims
To estimate quantitatively the association between dietary magnesium intake and risk of metabolic syndrome by combining the relevant published articles using meta-analysis.
Methods
We reviewed the relevant literature in PubMed and EMBASE published up until August 2013 and obtained additional information through Google or a hand search of the references in relevant articles. A random-effects or fixed-effects model, as appropriate, was used to pool the effect sizes on metabolic syndrome comparing individuals with the highest dietary magnesium intake with those having the lowest intake. The dose-response relationship was assessed for every 100-mg/day increment in magnesium intake and risk of metabolic syndrome.
Result
Six cross-sectional studies, including a total of 24 473 individuals and 6311 cases of metabolic syndrome, were identified as eligible for the meta-analysis. A weighted inverse association was found between dietary magnesium intake and the risk of metabolic syndrome (odds ratio 0.69, 95% CI 0.59, 0.81) comparing the highest with the lowest group. For every 100-mg/day increment in magnesium intake, the overall risk of having metabolic syndrome was lowered by 17% (odds ratio 0.83, 95% CI 0. 77, 0.89).
Conclusion
Findings from the present meta-analysis suggest that dietary magnesium intake is inversely associated with the prevalence of metabolic syndrome. Further studies, in particular well-designed longitudinal cohort studies and randomized placebo-controlled clinical trials, are warranted to provide solid evidence and to establish causal inference.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.