Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial
Veronese N, Berton L, Carraro S, Bolzetta F, De Rui M, Perissinotto E, Toffanello ED, Bano G, Pizzato S, Miotto F, Coin A, Manzato E, Sergi G
The American journal of clinical nutrition · 100 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-07-09 · Am J Clin Nutr · vol. 100 · número 3 · págs. 974–981
- Editorial
- Elsevier BV
- Citado
- 154 citas · más que el 99% de estudios similares · 10.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 43 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Magnesium in Health and Disease · Nutrition and Health in Aging · Nutrition and Health Studies
- Palabras clave
- magnesium supplementation, hypomagnesemia, physical performance, older women, exercise program, Short Physical Performance Battery, muscle strength, grip strength, walking speed, dietary magnesium, aging
- MeSH
- lower extremity, humans, magnesium deficiency, magnesium, magnesium oxide, gait, hand strength, exercise, geriatric assessment, severity of illness index, follow-up studies, double-blind method, psychomotor performance, aging, dietary supplements, aged, italy, female, muscle strength, performance-enhancing substances
13 autores
- Nicola Veronese🇮🇹University of Padua
- Linda Berton🇮🇹University of Padua
- Sara Carraro🇮🇹University of Padua
- Francesco Bolzetta🇮🇹University of Padua
- Marina DE RUI🇮🇹University of Padua
- Egle Perissinotto🇮🇹University of Padua
- Elena Debora Toffanello🇮🇹University of Padua
- Giulia Bano🇮🇹University of Padua
- Simona Pizzato🇮🇹University of Padua
- Fabrizia Miotto🇮🇹University of Padua
- Alessandra Coin🇮🇹University of Padua
- Enzo Manzato🇮🇹University of Padua
- Giuseppe Sergi🇮🇹University of Padua
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Magnesium deficiency is associated with poor physical performance, but no trials are available on how magnesium supplementation affects elderly people's physical performance.
Objective
The aim of our study was to investigate whether 12 wk of oral magnesium supplementation can improve physical performance in healthy elderly women.
Design
In a parallel-group, randomized controlled trial, 139 healthy women (mean ± SD age: 71.5 ± 5.2 y) attending a mild fitness program were randomly allocated to a treatment group (300 mg Mg/d; n = 62) or a control group (no placebo or intervention; n = 77) by using a computer-generated randomization sequence, and researchers were blinded to their grouping. After assessment at baseline and again after 12 wk, the primary outcome was a change in the Short Physical Performance Battery (SPPB); secondary outcomes were changes in peak torque isometric and isokinetic strength of the lower limbs and handgrip strength.
Results
A total of 124 participants allocated to the treatment (n = 53) or control (n = 71) group were considered in the final analysis. At baseline, the SPPB scores did not differ between the 2 groups. After 12 wk, the treated group had a significantly better total SPPB score (Δ = 0.41 ± 0.24 points; P = 0.03), chair stand times (Δ = -1.31 ± 0.33 s; P < 0.0001), and 4-m walking speeds (Δ = 0.14 ± 0.03 m/s; P = 0.006) than did the control group. These findings were more evident in participants with a magnesium dietary intake lower than the Recommended Dietary Allowance. No significant differences emerged for the secondary outcomes investigated, and no serious adverse effects were reported.
Conclusions
Daily magnesium oxide supplementation for 12 wk seems to improve physical performance in healthy elderly women. These findings suggest a role for magnesium supplementation in preventing or delaying the age-related decline in physical performance.
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