Nut consumption and the risk of coronary artery disease: a dose-response meta-analysis of 13 prospective studies
Ma L, Wang F, Guo W, Yang H, Liu Y, Zhang W
Thrombosis research · 14 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-07-05 · Thromb Res · vol. 134 · número 4 · págs. 790–794
- Editorial
- Elsevier BV
- Citado
- 22 citas · más que el 45% de estudios similares · 0.3× el promedio de su campo
- Referencias
- 29 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Cardiovascular Health and Risk Factors
- Palabras clave
- nut consumption, coronary artery disease, cardiovascular risk, dose-response relationship, dietary intake, protective effect, prospective cohort
- MeSH
- humans, nuts, risk factors, prospective studies, feeding behavior, adult, aged, aged, 80 and over, middle aged, female, male, coronary artery disease, young adult
6 autores
- Ling Ma🇨🇳Lanzhou Army General Hospital
- Fei Wang🇨🇳Lanzhou Army General Hospital
- Wenyun Guo🇨🇳Lanzhou Army General Hospital
- Hongning Yang🇨🇳Lanzhou Army General Hospital
- Yan Liu🇨🇳Lanzhou Army General Hospital
- Weize Zhang🇨🇳Lanzhou Army General Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Epidemiological studies evaluating the association of nut with risk of coronary artery disease (CAD) have produced inconsistent results. We conducted a meta-analysis to summarize the evidence from prospective cohort studies regarding the association between nut consumption and risk of CAD.
Materials and methods
Pertinent studies were identified by searching Web of Knowledge, Pubmed and Wan Fang Med Online up to January 2014. Random-effect model was used to combine the results. Dose-response relationship was assessed by restricted cubic spline. Publication bias was estimated using Begg' funnel plot and Egger's regression asymmetry test.
Results
Nine articles with 13 prospective studies involving 6,127 CAD cases and 347,477 participants were included in this meta-analysis. Pooled results suggested that highest nut consumption amount versus lowest amount was significantly associated with the risk of CAD [summary relative risk (RR)=0.660, 95%CI=0.581-0.748, I(2)=39.6%]. Linear dose-response relationship was found between nut consumption and CAD risk, and the risk of CAD decreased by 5% for every 1 serving/week increase intake of nut. A protective effect for CAD was found when consumed more than 2 servings/week of nut. The RR of CAD was 0.96 (0.89-1.02), 0.91 (0.82-0.99), 0.85 (0.77-0.95), 0.80 (0.72-0.89), 0.75 (0.65- 0.85) and 0.70 (0.58-0.83) for 1, 2, 3, 4, 5 and 6 servings/week of nut consumption, respectively.
Conclusions
Our analysis indicated that nut consumption has a protective effect on CAD.
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