A systematic review and meta-analysis on the efficacy of low-level laser therapy in the management of complication after mandibular third molar surgery
He WL, Yu FY, Li CJ, Pan J, Zhuang R, Duan PJ
Lasers in medical science · 57 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-08-06 · Lasers Med Sci · vol. 30 · número 6 · págs. 1779–1788
- Editorial
- Springer Science+Business Media
- Citado
- 96 citas · más que el 71% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Dental Radiography and Imaging · Dermatologic Treatments and Research
- Palabras clave
- low-level laser therapy, mandibular third molar extraction, impacted third molar, postoperative pain, trismus, facial swelling, postoperative complications, laser treatment efficacy, quality of evidence grading, patient satisfaction
- MeSH
- mandible, molar, third, humans, trismus, postoperative complications, treatment outcome, publication bias, adult, female, low-level light therapy, postoperative pain
6 autores
- Wenting He🇨🇳Guangdong Province Stomatological Hospital; Southern Medical University
- Feng Yu🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Chunjie Li🇨🇳Sichuan University; State Key Laboratory of Oral Diseases
- Jianke Pan🇨🇳Guangdong Province Stomatological Hospital; Southern Medical University
- Renkun Zhuang🇨🇳Guangdong Province Stomatological Hospital; Southern Medical University
- P. J. Duan🇨🇳 · autor de correspondenciaGuangdong Province Stomatological Hospital; Southern Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The successful reduction of postoperative discomfort is of great significance. This review aims to evaluate the efficacy of low-level laser therapy (LLLT) for the reduction of complication caused by impacted mandibular third molars extraction. An extensive literature search up to October 2013 for randomized controlled trials (RCTs) was performed through CENTRAL, PubMed, Embase, Medline, and CNKI. Six RCTs in which involves 193 participants are included in the meta-analysis. Among them, three RCTs exhibit a moderate risk of bias, while the other three show a high bias risk. Compared with placebo laser/control group, pain is significantly reduced with LLLT on the first day (mean difference [MD] = -2.63, 95% confidence interval [CI] -4.46 to -0.79, P = 0.005). The superiority of LLLT in pain control persists on the second day (MD = -2.34, 95% CI -4.61 to -0.06, P = 0.04) and the third day (MD = -3.40, 95% CI -4.12 to -2.68, P < 0.00001). Moreover, LLLT reduces an average of 4.94 mm (MD = 4.94, 95 % CI 1.53 to 8.34, P = 0.004) of trismus compared with placebo laser irradiation in the first 3 days. On the seventh day, the superiority of LLLT also persists (MD = 3.24, 95% CI 0.37 to 6.12, P = 0.03). In the first 3 days after surgery, extraoral irradiation (MD = -0.69, 95% CI -1.30 to -0.08, P = 0.03) and intraoral combined with extraoral irradiation (MD = -0.65, 95% CI -1.15 to -0.15, P = 0.01) reduced facial swelling significantly. On the seventh day, the intraoral combined with extraoral irradiation group (MD = -0.32, 95% CI -0.59 to -0.06, P = 0.02) still showed benefit in relieving facial swelling. However, because of the heterogeneity of intervention and outcomes assessment and risk of bias of included trials, the efficacy is proved with limited evidence. In the future, well-designed RCTs with larger sample size will be required to provide clearer recommendations.
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