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Ensayo controlado aleatorizado2014Financiación no declarada

Exercise training and music therapy in elderly with depressive syndrome: a pilot study

Verrusio W, Andreozzi P, Marigliano B, Renzi A, Gianturco V, Pecci MT, Ettorre E, Cacciafesta M, Gueli N

Complementary therapies in medicine · 26 citas

Etiquetas de revisión

Financiación no declarada

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2014-06-06 · Complement Ther Med · vol. 22 · número 4 · págs. 614–620
Editorial
Elsevier BV
Citado
59 citas · más que el 98% de estudios similares · 9.5× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
31 trabajos
Acceso
De pago
Áreas de investigación
Music Therapy and Health · Treatment of Major Depression · Physical Activity and Health
Palabras clave
exercise training, music therapy, depressive syndrome, older adults, mild to moderate depression, antidepressant treatment, anxiety, mood states, TNF-α, plasma cytokines, stress biomarkers, geriatric depression
MeSH
humans, anti-anxiety agents, treatment outcome, music therapy, exercise therapy, pilot projects, anxiety, depressive disorder, aged, aged, 80 and over, female, male

9 autores

  • Walter Verrusio🇮🇹 · autor de correspondenciaSapienza University of Rome
  • P. Andreozzi🇮🇹Sapienza University of Rome
  • Benedetta Marigliano🇮🇹Università Campus Bio-Medico; Campus Bio Medico University Hospital
  • Alessia Renzi🇮🇹Sapienza University of Rome
  • Vincenzo Gianturco🇮🇹Sapienza University of Rome
  • Maria Tecla Pecci🇮🇹Sapienza University of Rome
  • Evaristo Ettorre🇮🇹Sapienza University of Rome
  • Mauro Cacciafesta🇮🇹Sapienza University of Rome
  • Nicolò Gueli🇮🇹Sapienza University of Rome

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objective

Recent studies have thrown doubt on the true effectiveness of anti-depressants in light and moderate depression. The aim of this study is to evaluate the impact of physical training and music therapy on a sample group of subjects affected by light to moderate depression versus subjects treated with pharmacological therapy only.

Design and setting

Randomized controlled study. Patients were randomized into two groups. Subjects in the pharmacotherapy group received a therapy with antidepressant drugs; the exercise/music therapy group was assigned to receive physical exercise training combined with listening to music. The effects of interventions were assessed by differences in changes in mood state between the two groups.

Main outcome measures

Medically eligible patients were screened with the Hamilton Anxiety Scale and with the Geriatric Depression Scale. We used plasmatic cytokine dosage as a stress marker.

Results

We recruited 24 subjects (mean age: 75.5 ± 7.4, 11 M/13 F). In the pharmacotherapy group there was a significant improvement in anxiety only (p<0.05) at 6-months. In the exercise/music therapy was a reduction in anxiety and in depression at 3-months and at 6-months (p<0.05). We noted an average reduction of the level of TNF-a from 57.67 (± 39.37) pg/ml to 35.80 (± 26.18) pg/ml.

Conclusions

Our training may potentially play a role in the treatment of subjects with mild to moderate depression. Further research should be carried out to obtain more evidence on effects of physical training and music therapy in depressed subjects.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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