Effects of vitamin D supplementation on upper and lower body muscle strength levels in healthy individuals. A systematic review with meta-analysis
Tomlinson PB, Joseph C, Angioi M
Journal of science and medicine in sport · 117 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-08-11 · J Sci Med Sport · vol. 18 · número 5 · págs. 575–580
- Editorial
- Elsevier BV
- Citado
- 168 citas · más que el 81% de estudios similares · 1.7× el promedio de su campo
- Referencias
- 57 trabajos
- Acceso
- De pago
- Áreas de investigación
- Vitamin D Research Studies · Nutrition and Health Studies · Nutrition and Health in Aging
- Palabras clave
- vitamin D supplementation, muscle strength, upper limb strength, lower limb strength, healthy adults, serum vitamin D levels, muscle power, muscular endurance, maximal strength
- MeSH
- lower extremity, humans, vitamins, vitamin d, dietary supplements, adolescent, adult, female, male, muscle strength, randomized controlled trials as topic, young adult
3 autores
- Peter B. Tomlinson🇬🇧Queen Mary University of London
- Corey W. Joseph🇬🇧Queen Mary University of London
- Manuela Angioi🇬🇧 · autor de correspondenciaQueen Mary University of London
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
To investigate the effects of vitamin D supplementation on muscle strength in healthy individuals.
Design
A systematic review with meta-analysis.
Methods
In October 2013 a computerised literature search of three databases (PubMed, Web of Knowledge and Scopus) was performed. Included in the review were controlled and randomised controlled trials, published in English, which measured muscle strength and serum vitamin D concentration in participants 18-40 years old. References of identified articles were then cross-checked and citations scanned for additional articles. Quality was assessed using the PEDro scale. Muscle strength and vitamin D levels were extracted for a meta-analysis on upper and lower limb strength with standardised mean differences calculated to analyse effect.
Results
Six randomised controlled trials and one controlled trial were identified and quality assessment showed all seven trials were of 'good quality'. Data was extracted from 310 adults, 67% female, with mean ages ranging from 21.5 to 31.5 years. Trials lasted from 4 weeks to 6 months and dosages differed from 4000 IU per day to 60,000 IU per week. Upper and lower limb muscle strength had a standardised mean difference of 0.32 (95% CI=0.10, 0.54) and 0.32 (95% CI=0.01, 0.63) respectively, suggesting vitamin D supplementation significantly increased muscle strength in the experimental group for upper (P=0.005) and lower limbs (P=0.04).
Conclusions
Vitamin D supplementation increases upper and lower limb strength. Further research should focus on its effect on muscle power, endurance and maximal strength.
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