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Cholesterol and egg intakes and the risk of type 2 diabetes: the Japan Public Health Center-based Prospective Study

Kurotani K, Nanri A, Goto A, Mizoue T, Noda M, Oba S, Sawada N, Tsugane S, Japan Public Health Center-based Prospective Study Group

The British journal of nutrition · 34 citas

Etiquetas de revisión

Cuestionario de frecuencia de consumoSin ajuste declarado por estilo de vida

Datos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.

Cómo se estudió

Diseño
Estudio de cohortes (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte
Consumo medido con
Cuestionario de frecuencia de consumo

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Center for Global Health and Medicine
Gobierno
Ministry of Health, Labour and Welfare
Universidad u hospital
Tokyo University of Agriculture
Universidad u hospital
Tokyo Medical and Dental University
Gobierno
Japan Society for the Promotion of Science
Subvenciones
Ministry of Health, Labour and Welfare (H19‐016); Ministry of Health, Labour and Welfare (19shi-2); Japan Society for the Promotion of Science (25871168)

Según 5 financiadores declarados.

Publicación

Publicado
2014-09-18 · Br J Nutr · vol. 112 · número 10 · págs. 1636–1643
Editorial
Cambridge University Press
Citado
41 citas · más que el 94% de estudios similares · 4.0× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
30 trabajos
Acceso
Lectura gratuita
Áreas de investigación
Nutritional Studies and Diet · Diet and metabolism studies · Diet, Metabolism, and Disease
Palabras clave
Medicine, Quartile, Type 2 diabetes, Diabetes mellitus, Prospective cohort study, Odds ratio, Cholesterol, Logistic regression, Internal medicine, Risk factor, Endocrinology, Confidence interval
MeSH
humans, diabetes mellitus, type 2, cholesterol, dietary, diet, logistic models, odds ratio, risk factors, prospective studies, sex factors, postmenopause, eggs, adult, middle aged, japan, female, male, self report, surveys and questionnaires

8 autores

  • Kayo Kurotani🇯🇵 · autor de correspondenciaNational Center for Global Health and Medicine
  • Akiko Nanri🇯🇵National Center for Global Health and Medicine
  • Atsushi Goto🇯🇵National Center for Global Health and Medicine
  • Tetsuya Mizoue🇯🇵National Center for Global Health and Medicine
  • Mitsuhiko Noda🇯🇵National Center for Global Health and Medicine
  • Shino Oba🇯🇵National Institute of Public Health
  • Norie Sawada🇺🇸Prevention Group
  • Shoichiro Tsugane🇺🇸Prevention Group

Resumen

El texto original del estudio, en el idioma en que se publicó.

Limited and inconsistent associations between cholesterol and egg consumption and type 2 diabetes risk have been observed in Western countries. In the present study, the association of dietary cholesterol and egg intakes with type 2 diabetes risk was examined prospectively. The study subjects comprised 27, 248 men and 36,218 women aged 45-75 years who participated in the second survey of the Japan Public Health Center-based Prospective Study and had no histories of type 2 diabetes or other serious diseases. Dietary cholesterol and egg intakes were estimated using a validated 147-item FFQ. The OR of self-reported, physician-diagnosed type 2 diabetes over 5 years were estimated using multiple logistic regression. A total of 1165 newly diagnosed cases of type 2 diabetes were self-reported. Although dietary cholesterol intake was not associated with type 2 diabetes risk in men, it was found to be associated with a 23 % lower odds of type 2 diabetes risk in women in the highest quartile of intake, albeit not statistically significant, compared with those in the lowest quartile (P trend= 0·08). Such risk reduction was somewhat greater among postmenopausal women; the multivariable-adjusted OR for the highest quartile of cholesterol intake compared with the lowest quartile was 0·68 (95 % CI 0·49, 0·94; P trend= 0·04). No association between egg intake and type 2 diabetes risk was found in either men or women. In conclusion, higher intake of cholesterol or eggs may not be associated with an increased risk of type 2 diabetes in Japanese populations. The observed association between decreased type 2 diabetes risk and higher dietary cholesterol intake in postmenopausal women warrants further investigation.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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