Nut consumption has favorable effects on lipid profiles of Korean women with metabolic syndrome
Lee YJ, Nam GE, Seo JA, Yoon T, Seo I, Lee JH, Im D, Bahn KN, Jeong SA, Kang TS, Ahn JH, Kim DH, Kim NH
Nutrition research (New York, N.Y.) · 47 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Ministry of Food and Drug Safety
- Subvenciones
- Ministry of Food and Drug Safety (12161MFDS118)
Según 1 financiador declarado.
Publicación
- Publicado
- 2014-08-30 · Nutr Res · vol. 34 · número 9 · págs. 814–820
- Editorial
- Elsevier BV
- Citado
- 58 citas · más que el 86% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 36 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nuts composition and effects · Nutritional Studies and Diet · Fatty Acid Research and Health
- Palabras clave
- nut consumption, mixed nuts, metabolic syndrome, lipid profile, total cholesterol, non-HDL cholesterol, Juglans regia, groundnut, pine nuts, dietary supplementation, inflammation, oxidative stress, endothelial function, Korean women
- MeSH
- endothelium, vascular, humans, juglans, pinus, nuts, cardiovascular diseases, inflammation, cholesterol, lipoproteins, hdl, body mass index, diet, feeding behavior, oxidative stress, dietary supplements, adult, aged, middle aged, female, republic of korea, arachis, metabolic syndrome, asian people
13 autores
- Young Ju Lee🇰🇷National Institute of Food and Drug Safety Evaluation
- Ga Eun Nam🇰🇷 · autor de correspondenciaKorea University Ansan Hospital
- Ji A Seo🇰🇷Korea University Ansan Hospital
- Taehyung Yoon🇰🇷National Institute of Food and Drug Safety Evaluation
- Ilwon Seo🇰🇷National Institute of Food and Drug Safety Evaluation
- Jin Hee Lee🇰🇷National Institute of Food and Drug Safety Evaluation
- Donggil Im🇰🇷National Institute of Food and Drug Safety Evaluation
- Kyeong-Nyeo Bahn🇰🇷National Institute of Food and Drug Safety Evaluation
- Si An Jeong🇰🇷National Institute of Food and Drug Safety Evaluation
- Tae Seok Kang🇰🇷National Institute of Food and Drug Safety Evaluation
- Jae Hee Ahn🇰🇷Korea University Ansan Hospital
- Do‐Hoon Kim🇰🇷Korea University Ansan Hospital
- Nan Hee Kim🇰🇷 · autor de correspondenciaKorea University Ansan Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Nut consumption has been studied for its cardioprotective effects. However, the findings of clinical intervention studies are inconsistent; and no intervention studies have been conducted in the Korean population. We hypothesized that nut supplementation may have favorable influence on metabolic markers. Therefore, this study aimed to investigate the effects of nut consumption on metabolic parameters and biomarkers related to inflammation, oxidative stress, and endothelial function in Korean adults with metabolic syndrome. To this end, we designed a randomized, parallel, controlled dietary intervention study (ClinicalTrials.gov NCT02023749). Subjects with metabolic syndrome and a body mass index of at least 23 kg/m(2) were randomized to the Control group and the Nut group, which received supplementation with 30 g/d of mixed nuts (walnuts, peanuts, and pine nuts) for 6 weeks. Sixty volunteers were included in the final analysis. Metabolic markers were evaluated at baseline and at the end of the study. Total cholesterol and non-high-density lipoprotein cholesterol levels significantly improved in the Nut group compared to those in the Control group (P = .023 and P = .016, respectively) in women. Biomarkers related to inflammation, oxidative stress, and endothelial function did not significantly change from baseline in either group. Thus, supplementing a usual diet with mixed nuts for 6 weeks had favorable effects on several lipid parameters in Korean women with metabolic syndrome. These findings present a possible mechanism for the cardioprotective effects of nut consumption.
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