Chromium in drinking water: association with biomarkers of exposure and effect
Sazakli E, Villanueva CM, Kogevinas M, Maltezis K, Mouzaki A, Leotsinidis M
International journal of environmental research and public health · 24 citas
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2014-09-29 · Int J Environ Res Public Health · vol. 11 · número 10 · págs. 10125–10145
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 43 citas · más que el 84% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 50 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Chromium effects and bioremediation · Adsorption and biosorption for pollutant removal · Mercury impact and mitigation studies
- Palabras clave
- Environmental health, Association (psychology), Chromium, Exposure assessment, Medicine, Environmental chemistry, Chemistry, Psychology
- MeSH
- hair, humans, sodium, chromium, triglycerides, water pollutants, chemical, diet, cross-sectional studies, motor activity, water supply, adult, aged, middle aged, greece, female, male, drinking water, biomarkers
6 autores
- Eleni Sazakli🇬🇷University of Patras
- Cristina M. Villanueva🇪🇸Universitat Pompeu Fabra; Center for Research in Environmental Epidemiology; Hospital Del Mar; Municipal Institute for Medical Research; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública; Hospital del Mar Research Institute
- Manolis Kogevinas🇪🇸🇬🇷Universitat Pompeu Fabra; Center for Research in Environmental Epidemiology; National School of Public Health; Hospital Del Mar; Municipal Institute for Medical Research; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública; Hospital del Mar Research Institute
- Kyriakos Maltezis
- Αthanasia Mouzaki🇬🇷University of Patras
- Michalis Leotsinidis🇬🇷 · autor de correspondenciaUniversity of Patras
Resumen
El texto original del estudio, en el idioma en que se publicó.
An epidemiological cross-sectional study was conducted in Greece to investigate health outcomes associated with long-term exposure to chromium via drinking water. The study population consisted of 304 participants. Socio-demographics, lifestyle, drinking water intake, dietary habits, occupational and medical history data were recorded through a personal interview. Physical examination and a motor test were carried out on the individuals. Total chromium concentrations were measured in blood and hair of the study subjects. Hematological, biochemical and inflammatory parameters were determined in blood. Chromium in drinking water ranged from <0.5 to 90 μg·L-1 in all samples but one (220 μg·L-1), with a median concentration of 21.2 μg·L-1. Chromium levels in blood (median 0.32 μg·L-1, range <0.18-0.92 μg·L-1) and hair (median 0.22 μg·g-1, range 0.03-1.26 μg·g-1) were found within "normal range" according to the literature. Personal lifetime chromium exposure dose via drinking water, calculated from the results of the water analyses and the questionnaire data, showed associations with blood and hair chromium levels and certain hematological and biochemical parameters. Groups of subjects whose hematological or biochemical parameters were outside the normal range were not correlated with chromium exposure dose, except for groups of subjects with high triglycerides or low sodium. Motor impairment score was not associated with exposure to chromium.
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