Effects of Creatine and Resistance Training on Bone Health in Postmenopausal Women
Chilibeck PD, Candow DG, Landeryou T, Kaviani M, Paus-Jenssen L
Medicine and science in sports and exercise · 61 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-11-11 · Med Sci Sports Exerc · vol. 47 · número 8 · págs. 1587–1595
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 87 citas · más que el 91% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 52 trabajos
- Acceso
- De pago
- Áreas de investigación
- Bone health and osteoporosis research · Muscle metabolism and nutrition · Nutrition and Health in Aging
- Palabras clave
- creatine supplementation, resistance training, bone mineral density, postmenopausal women, femoral neck bone loss, lumbar spine bone mineral density, muscle strength, bone health
- MeSH
- humans, creatine, double-blind method, postmenopause, bone density, middle aged, female, resistance training, outcome assessment, health care
5 autores
- Philip David Chilibeck🇨🇦University of Regina; University of Saskatchewan
- Darren Glenn Candow🇨🇦University of Regina
- Tim Landeryou🇨🇦University of Saskatchewan
- Mojtaba Kaviani🇨🇦University of Saskatchewan
- Lisa Paus-Jenssen🇨🇦University of Saskatchewan
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Our primary purpose was to determine the effect of 12 months of creatine (Cr) supplementation during a supervised resistance training program on properties of bone in postmenopausal women.
Methods
Participants were randomized (double-blind) into two groups: resistance training (3 d·wk) and Cr supplementation (0.1 g·kg·d) or resistance training and placebo (Pl). Our primary outcome measures were lumbar spine and femoral neck bone mineral density (BMD). Secondary outcome measures were total hip and whole-body BMD, bone geometric properties at the hip, speed of sound at the distal radius and tibia, whole-body lean tissue mass, muscle thickness, and bench press and hack squat strength. Forty-seven women (57 (SD, 6) yr; Cr, n = 23; Pl, n = 24) were randomized, with 33 analyzed after 12 months (Cr, n = 15; Pl, n = 18).
Results
Cr attenuated the rate of femoral neck BMD loss (-1.2%; absolute change (95% confidence interval), -0.01 (-0.025 to 0.005) g·cm) compared with Pl (-3.9%; -0.03 (-0.044 to -0.017) g·cm; P < 0.05) and also increased femoral shaft subperiosteal width, a predictor of bone bending strength (Cr, 0.04 (-0.09 to 0.16) cm); Pl, -0.12 (-0.23 to -0.01) cm; P < 0.05). Cr increased relative bench press strength more than Pl (64% vs 34%; P < 0.05). There were no differences between groups for other outcome measures. There were no differences between groups for reports of serum liver enzyme abnormalities, and creatinine clearance was normal for Cr participants throughout the intervention.
Conclusions
Twelve months of Cr supplementation during a resistance training program preserves femoral neck BMD and increases femoral shaft superiosteal width, a predictor of bone bending strength, in postmenopausal women.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.