Effect of low-level laser therapy on pain and swelling in women with breast cancer-related lymphedema: a systematic review and meta-analysis
Smoot B, Chiavola-Larson L, Lee J, Manibusan H, Allen DD
Journal of cancer survivorship : research and practice · 70 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Center for Advancing Translational Sciences
- Gobierno
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Gobierno
- NCATS NIH HHS
- Gobierno
- NICHD NIH HHS
- Subvenciones
- National Center for Advancing Translational Sciences (KL2-TR-000143); Eunice Kennedy Shriver National Institute of Child Health and Human Development (K12HD052163)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2014-11-29 · J Cancer Surviv · vol. 9 · número 2 · págs. 287–304
- Editorial
- Springer Science+Business Media
- Citado
- 112 citas · más que el 68% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 36 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Lymphatic System and Diseases · Dermatologic Treatments and Research
- Palabras clave
- low-level laser therapy, breast cancer-related lymphedema, arm lymphedema, limb volume reduction, analgesia, swelling, breast cancer survivors
- MeSH
- humans, breast neoplasms, pain, lymphedema, treatment outcome, mastectomy, adult, survivors, female, pain management, low-level light therapy
5 autores
- Betty J. Smoot🇺🇸 · autor de correspondenciaUniversity of California, San Francisco; San Francisco State University
- Laura Chiavola-Larson🇺🇸Dominican Hospital
- Jeannette Y. Lee🇺🇸University of California, San Francisco; San Francisco State University
- Hidelisa Manibusan🇺🇸University of California, San Francisco
- Diane D. Allen🇺🇸University of California, San Francisco; San Francisco State University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
This study aims to examine literature on effectiveness of low-level laser therapy (LLLT) in reducing limb volume and pain in adults with breast cancer-related lymphedema (BCRL).
Methods
PubMed, PEDro, CINAHL, and Cochrane databases were searched using (lymphedema OR edema OR swelling) AND (breast cancer OR mastectomy) AND (laser OR low-level laser therapy OR LLLT OR cold laser). Intervention studies or meta-analyses reporting LLLT for BCRL were included in the search. Pooled effect sizes (ES) and 95 % confidence intervals (CI) were calculated for volume and pain. No limitations were placed on length of follow-up, publication year, or language. Final search was conducted on October 16, 2014.
Results
Nine studies met criteria for inclusion. Within-group pooled ES for volume (six studies) was -0.52 (-0.78, -0.25), representing a 75.7-ml reduction in limb volume after LLLT. Between-group pooled ES for volume (four studies) was -0.62 (-0.97, -0.28), representing a 90.9-ml greater reduction in volume with treatment including LLLT versus not including LLLT. Within-group pooled ES for pain reduction (three studies) was -0.62 (-1.06, -0.19), pain reduction of 13.5 mm (0-100 mm VAS). Between-group pooled ES for pain reduction (two studies) was non-significant at -1.21 (-4.51, 2.10).
Conclusion
Moderate-strength evidence supports LLLT in the management of BCRL, with clinically relevant within-group reductions in volume and pain immediately after conclusion of LLLT treatments. Greater reductions in volume were found with the use of LLLT than in treatments without it.
Implications for cancer survivors
LLLT confers clinically meaningful reductions in arm volume and pain in women with BCRL.
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