Dietary magnesium intake and metabolic syndrome in the adult population: dose-response meta-analysis and meta-regression
Ju SY, Choi WS, Ock SM, Kim CM, Kim DH
Nutrients · 45 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Catholic University of Korea
- Universidad u hospital
- College of Medicine, Catholic University of Korea
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2014-12-22 · Nutrients · vol. 6 · número 12 · págs. 6005–6019
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 69 citas · más que el 92% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 66 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Therapeutic Uses of Natural Elements · Parathyroid Disorders and Treatments
- Palabras clave
- Meta-analysis, Meta-regression, Medicine, Magnesium, Population, Physiology, Metabolic syndrome, Internal medicine, Endocrinology, Biology, Food science, Obesity, Environmental health, Chemistry
- MeSH
- humans, magnesium, risk assessment, risk factors, dose-response relationship, drug, observational studies as topic, metabolic syndrome
5 autores
- Sang-Yhun Ju🇰🇷The Catholic University of Korea Yeouido St. Mary's Hospital; Catholic University of Korea
- Whan-Seok Choi🇺🇸🇬🇧🇰🇷St. Mary's Hospital; St Mary's Hospital; The Catholic University of Korea Seoul St. Mary's Hospital; Catholic University of Korea
- Sun-Myeong Ock🇰🇷The Catholic University of Korea Yeouido St. Mary's Hospital
- Chul-Min Kim🇺🇸🇬🇧🇰🇷St. Mary's Hospital; St Mary's Hospital; The Catholic University of Korea Seoul St. Mary's Hospital
- Do‐Hoon Kim🇰🇷Korea University; Ansan University; Korea University Ansan Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
ncreasing evidence has suggested an association between dietary magnesium intake and metabolic syndrome. However, previous research examining dietary magnesium intake and metabolic syndrome has produced mixed results. Our objective was to determine the relationship between dietary magnesium intake and metabolic syndrome in the adult population using a dose-response meta-analysis. We searched the PubMed, Embase and the Cochrane Library databases from August, 1965, to May, 2014. Observational studies reporting risk ratios with 95% confidence intervals (CIs) for metabolic syndrome in ≥ 3 categories of dietary magnesium intake levels were selected. The data extraction was performed independently by two authors, and the quality of the studies was evaluated using the Risk of Bias Assessment Tool for Nonrandomized Studies (RoBANS). Based on eight cross-sectional studies and two prospective cohort studies, the pooled relative risks of metabolic syndrome per 150 mg/day increment in magnesium intake was 0.88 (95% CI, 0.84-0.93; I(2) = 36.3%). The meta-regression model showed a generally linear, inverse relationship between magnesium intake (mg/day) and metabolic syndrome. This dose-response meta-analysis indicates that dietary magnesium intake is significantly and inversely associated with the risk of metabolic syndrome. However, randomized clinical trials will be necessary to address the issue of causality and to determine whether magnesium supplementation is effective for the prevention of metabolic syndrome.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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