Meta-analysis of the association between whole grain intake and coronary heart disease risk
Tang G, Wang D, Long J, Yang F, Si L
The American journal of cardiology · 64 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2014-12-19 · Am J Cardiol · vol. 115 · número 5 · págs. 625–629
- Editorial
- Elsevier BV
- Citado
- 95 citas · más que el 85% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 32 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Food composition and properties · Cardiovascular Health and Risk Factors
- Palabras clave
- whole grain intake, coronary artery disease, cardiovascular risk, dietary protection, dietary fiber, cohort studies, case-control study
- MeSH
- humans, coronary disease, diet, case-control studies, cohort studies, edible grain
5 autores
- Gang Tang🇨🇳Army Medical University; Southwest Hospital
- Duan Wang🇨🇳Army Medical University; Southwest Hospital
- Jun Long🇨🇳Army Medical University; Southwest Hospital
- Fan Yang🇨🇳Army Medical University; Southwest Hospital
- Liang‐Yi Si🇨🇳 · autor de correspondenciaArmy Medical University; Southwest Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Epidemiologic studies evaluating the association of whole-grain intake with risk for coronary heart disease (CHD) have produced inconsistent results. The aim of this meta-analysis was to summarize the evidence from observed studies regarding the association between whole-grain intake and risk for CHD. Pertinent studies were identified by searching the Web of Knowledge and PubMed up to July 2014. A random-effects model was used to combine the results. Publication bias was estimated using Begg's funnel plot and Egger's regression asymmetry test. Ultimately, fourteen reports of 18 studies (15 cohort studies and 3 case-control studies) involving 14,427 patients with CHD and 400,492 participants were used in this meta-analysis. Pooled results suggested that highest whole-grain intake amount compared with the lowest amount was significantly associated with reduced risk for CHD (summary relative risk 0.787, 95% confidence interval 0.743 to 0.833), with no between-study heterogeneity observed (I(2) = 0%, p = 0.537). The association was significant in cohort studies but not in case-control studies. Inverse associations were also found in the United States and Europe. No publication bias was found. In conclusion, this meta-analysis indicates that higher whole-grain intake has a protective effect against CHD.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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