Creatine supplementation alters homocysteine level in resistance trained men
Bereket-Yücel S
The Journal of sports medicine and physical fitness · 4 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2015-04-01 · J Sports Med Phys Fitness · vol. 55 · número 4 · págs. 313–9
- Editorial
- National Institutes of Health
- Citado
- 9 citas · más que el 65% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 0 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Folate and B Vitamins Research · Biochemical effects in animals
- Palabras clave
- creatine supplementation, homocysteine, resistance training, serum lipids, folic acid, vitamin B12, cardiovascular risk factors, body composition, young men
- MeSH
- humans, creatine, homocysteine, double-blind method, dietary supplements, male, resistance training, young adult
1 autor
- Selda Bereket Yücel🇹🇷 · autor de correspondenciaManisa Celal Bayar University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Aim
This study was conducted to investigate the effects of creatine loading and resistance training on the homocysteine and lipid profiles of young males.
Method
Sixty male University students (22.34 ± 2.19 years, 1.79 ± 0.08 m, 77.18 ± 12.57 kg, 15.48 ± 4.57% body fat) were randomly divided in to three groups; control (CG=20), creatine supplement (CEG=20) and placebo (PEG=20). Both CEG and PEG participated in a same resistance-training regimen and either taking a creatine supplement (25 g/d for the first 5 days followed 5 g/d thereafter) or the same amount of placebo for 8 weeks. Participants in CG did not take any creatine supplementation and not engage any exercise program. After the body composition were assessed, the homocysteine (Hcy) concentrations, blood lipids, folic acid and vitamin B12 levels of all the participants were measured at the beginning and end of the eight weeks of resistance training.
Results
The analysis of the data indicated that the Hcy levels of the CEG after resistance training and receiving the creatine supplement (9.33 ± 4.60) was significantly lower than that of baseline (12.66 ± 5.89) measurements, F(1,18)=12.28, P=0.00. No significant differences were seen in the Hcy levels of the PEG (15.01 ± 10.87) after 8 weeks of training and receiving a placebo (12.46 ± 12.50), F(1,16)=4.65, P=0.05. Furthermore, there were no significant differences among groups in terms of Hcy levels, F(2,52)=1.72, P=0.19.
Conclusion
The present study suggests that as well as strength gain; creatine supplementation with resistance training may afford some protection against emerging cardiovascular risk factors.
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