Creatine Supplementation and Lower Limb Strength Performance: A Systematic Review and Meta-Analyses
Lanhers C, Pereira B, Naughton G, Trousselard M, Lesage FX, Dutheil F
Sports medicine (Auckland, N.Z.) · 103 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2015-05-06 · Sports Med · vol. 45 · número 9 · págs. 1285–1294
- Editorial
- Springer Science+Business Media
- Citado
- 188 citas · más que el 64% de estudios similares · 0.9× el promedio de su campo
- Referencias
- 100 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
- Palabras clave
- creatine supplementation, upper limb strength, bench press, chest press, creatine loading
- MeSH
- leg, humans, creatine, dietary supplements, adolescent, adult, aged, middle aged, female, male, muscle strength, young adult
6 autores
- Charlotte Lanhers🇫🇷Centre Hospitalier Universitaire de Clermont-Ferrand
- Bruno Pereira🇫🇷Centre Hospitalier Universitaire de Clermont-Ferrand
- Geraldine A. Naughton🇦🇺Australian Catholic University
- Marion Trousselard🇫🇷Service de Santé des Armées
- François‐Xavier Lesage🇫🇷Centre Hospitalier Universitaire de Montpellier
- Frédéric Dutheil🇫🇷🇦🇺 · autor de correspondenciaCentre Hospitalier Universitaire de Clermont-Ferrand; Centre de Recherche en Nutrition Humaine d'Auvergne; Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques; Université Blaise Pascal; Australian Catholic University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Creatine is the most widely used supplementation to increase strength performance. However, the few meta-analyses are more than 10 years old and suffer from inclusion bias such as the absence of randomization and placebo, the diversity of the inclusion criteria (aerobic/endurance, anaerobic/strength), no evaluation on specific muscles or group of muscles, and the considerable amount of conflicting results within the last decade.
Objective
The objective of this systematic review was to evaluate meta-analyzed effects of creatine supplementation on lower limb strength performance.
Methods
We conducted a systematic review and meta-analyses of all randomized controlled trials comparing creatine supplementation with a placebo, with strength performance of the lower limbs measured in exercises lasting less than 3 min. The search strategy used the keywords "creatine supplementation" and "performance". Dependent variables were creatine loading, total dose, duration, the time-intervals between baseline (T0) and the end of the supplementation (T1), as well as any training during supplementation. Independent variables were age, sex, and level of physical activity at baseline. We conducted meta-analyses at T1, and on changes between T0 and T1. Each meta-analysis was stratified within lower limb muscle groups and exercise tests.
Results
We included 60 studies (646 individuals in the creatine supplementation group and 651 controls). At T1, the effect size (ES) among stratification for squat and leg press were, respectively, 0.336 (95 % CI 0.047-0.625, p = 0.023) and 0.297 (95 % CI 0.098-0.496, p = 0.003). Overall quadriceps ES was 0.266 (95 % CI 0.150-0.381, p < 0.001). Global lower limb ES was 0.235 (95 % CI 0.125-0.346, p < 0.001). Meta-analysis on changes between T0 and T1 gave similar results. The meta-regression showed no links with characteristics of population or of supplementation, demonstrating the creatine efficacy effects, independent of all listed conditions.
Conclusion
Creatine supplementation is effective in lower limb strength performance for exercise with a duration of less than 3 min, independent of population characteristic, training protocols, and supplementary doses and duration.
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