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Influence of postoperative low-level laser therapy on the osseointegration of self-tapping implants in the posterior maxilla: a 6-week split-mouth clinical study

Mandić B, Lazić Z, Marković A, Mandić B, Mandić M, Djinić A, Miličić B

Vojnosanitetski pregled · 30 citas

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2014-12-01 · Vojnosanit Pregl · vol. 72 · número 3 · págs. 233–240
Editorial
Military Health Department, Ministry of Defance, Serbia
Citado
45 citas · más que el 77% de estudios similares · 1.1× el promedio de su campo
Referencias
27 trabajos
Acceso
Acceso abierto (revista) · CC-BY-SA
Áreas de investigación
Dental Implant Techniques and Outcomes · Laser Applications in Dentistry and Medicine · Bone Tissue Engineering Materials
Palabras clave
low-level laser therapy, osseointegration, posterior maxilla, osteopenia, implant stability, alkaline phosphatase, GaAlAs laser
MeSH
maxilla, humans, dental implants, postoperative care, dental implantation, endosseous, dental prosthesis design, aged, middle aged, female, male, low-level light therapy

7 autores

  • Borka Mandic🇷🇸University of Belgrade
  • Zoran Lazić🇷🇸Military Medical Academy; University of Defence
  • M. Aleksa🇷🇸University of Belgrade
  • Bojan Mandić🇷🇸University of Belgrade
  • Miska Mandic🇷🇸University of Belgrade
  • Ana Djinic Krasavcevic🇷🇸University of Belgrade
  • Biljana Miličić🇷🇸University of Belgrade

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background/aim

Low-level laser therapy (LLLT) has been proven to stimulate bone repair, affecting cellular proliferation, differentiation and adhesion, and has shown a potential to reduce the healing time following implant placement. The aim of this clinical study was to investigate the influence of postoperative LLLT osseointegration and early success of self-tapping implants placed into low-density bone.

Methods

Following the split-mouth design, self-tapping implants n = 44) were inserted in the posterior maxilla of 12 patients. One jaw side randomly received LLLT (test group), while the other side was placebo (control group). For LLLT, a 637 nm gallium-aluminum-arsenide (GaAlAs) laser (Medicolaser 637, Technoline, Belgrade, Serbia) with an output power of 40 mW and continuous wave was used. Low-level laser treatment was performed immediately after the surgery and then repeated every day in the following 7 days. The total irradiation dose per treatment was 6.26 J/cm2 per implant. The study outcomes were: implant stability, alkaline-phosphatase (ALP) activity and early implant success rate. The follow-up took 6 weeks.

Results

Irradiated implants achieved a higher stability compared with controls during the entire follow-up and the difference reached significance in the 5th postoperative week (paired t-test, p = 0.030). The difference in ALP activity between the groups was insignificant in any observation point (paired t-test, p > 0.05). The early implant success rate was 100%, regardless of LLLT usage.

Conclusion

LLLT applied daily during the first postoperative week expressed no significant influence on the osseointegration of self-tapping implants placed into low density bone of the posterior maxilla. Placement of self-tapping macro-designed implants into low density bone could be a predictable therapeutic procedure with a high early success rate regardless of LLLT usage.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-SA).

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