Pre-diagnostic cruciferous vegetables intake and lung cancer survival among Chinese women
Wu QJ, Yang G, Zheng W, Zheng W, Li HL, Gao J, Wang J, Gao YT, Shu XO, Xiang YB
Scientific reports · 13 citas
Etiquetas de revisión
Sin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Vanderbilt University
- Gobierno
- National Institutes of Health
- Gobierno
- National Cancer Institute
- Gobierno
- Fogarty International Center
- Gobierno
- NCI NIH HHS
- Gobierno
- FIC NIH HHS
- Subvenciones
- National Cancer Institute (UM1 CA182910); National Cancer Institute (R37-CA070867); Fogarty International Center (D43 TW008313); National Institutes of Health (R37CA070867)
Según 6 financiadores declarados.
Publicación
- Publicado
- 2015-05-19 · Sci Rep · vol. 5 · número 1 · pág. 10306
- Editorial
- Nature Portfolio
- Citado
- 16 citas · más que el 71% de estudios similares · 0.7× el promedio de su campo
- Referencias
- 36 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Genomics, phytochemicals, and oxidative stress · Nitrogen and Sulfur Effects on Brassica · Cancer, Lipids, and Metabolism
- Palabras clave
- Cruciferous vegetables, Medicine, Lung cancer, Interquartile range, Hazard ratio, Quartile, Proportional hazards model, Internal medicine, Confounding, Confidence interval, Cancer
- MeSH
- humans, vegetables, lung neoplasms, diet, risk factors, cohort studies, prospective studies, life style, adult, aged, middle aged, china, female, surveys and questionnaires
9 autores
- Qi‐Jun Wu🇨🇳Renji Hospital; Shanghai Cancer Institute; State Key Laboratory of Oncogene and Related Genes; China Medical University
- Gong Yang🇺🇸Vanderbilt University
- Wei Zheng🇺🇸Vanderbilt University
- Honglan Li🇨🇳Renji Hospital; Shanghai Cancer Institute; State Key Laboratory of Oncogene and Related Genes
- Jing Gao🇨🇳Renji Hospital; Shanghai Cancer Institute; State Key Laboratory of Oncogene and Related Genes
- Jing Wang🇨🇳Renji Hospital; Shanghai Cancer Institute; State Key Laboratory of Oncogene and Related Genes
- Yu‐Tang Gao🇨🇳Renji Hospital; Shanghai Cancer Institute; State Key Laboratory of Oncogene and Related Genes
- Xiao‐Ou Shu🇺🇸Vanderbilt University
- Yong‐Bing Xiang🇨🇳Renji Hospital; Shanghai Cancer Institute; State Key Laboratory of Oncogene and Related Genes
Resumen
El texto original del estudio, en el idioma en que se publicó.
No study to date has prospectively evaluated the association between pre-diagnostic cruciferous vegetables intake and lung cancer survival among women. This analysis included 547 incident lung cancer cases identified from the Shanghai Women's Health Study (SWHS) during the follow-up period of 1997-2011. Dietary intake was assessed for all SWHS participants at enrollment and reassessed 2-3 years later. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for potential confounders. Of the 547 lung cancer patients, 412 patients died during the follow-up. A total of 393 (95.4%) deaths from lung cancer were documented with median survival time of 10.3 months (interquartile range, 3.6-21.1 months). High cruciferous vegetables intake was significantly associated with improved lung cancer-specific survival after adjusting for all nonclinical prognostic factors (n = 547, HR = 0.69; 95%CI = 0.49-0.95; P trend = 0.02) for the highest versus lowest quartile. A slightly stronger association of cruciferous vegetables intake with lung cancer-specific survival was observed in analyses restricted to patients with known clinical prognostic factors (n = 331, HR = 0.63; 95%CI = 0.41-0.97; P trend = 0.03) or never smokers (n = 308, HR = 0.58; 95%CI = 0.37-0.91; P trend = 0.02). In conclusion, pre-diagnostic cruciferous vegetables intake is associated with better survival of lung cancer in Chinese women.
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