Strategic creatine supplementation and resistance training in healthy older adults
Candow DG, Vogt E, Johannsmeyer S, Forbes SC, Farthing JP
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 71 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2015-02-26 · Appl Physiol Nutr Metab · vol. 40 · número 7 · págs. 689–694
- Editorial
- NRC Research Press
- Citado
- 120 citas · más que el 87% de estudios similares · 2.2× el promedio de su campo
- Referencias
- 46 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Nutrition and Health in Aging
- Palabras clave
- Creatine, Placebo, Lean body mass, Creatine Monohydrate, Resistance training, Leg press, Medicine, One-repetition maximum, Internal medicine, Endocrinology, Animal science, Body weight, Biology, Pathology
- MeSH
- humans, creatine, absorptiometry, photon, double-blind method, body composition, aging, dietary supplements, aged, middle aged, female, male, muscle strength, resistance training
5 autores
- Darren Glenn Candow🇨🇦University of Regina
- Emelie Vogt🇨🇦University of Regina
- Sarah Johannsmeyer🇨🇦University of Regina
- Scott C. Forbes🇨🇦Okanagan College
- Jonathan P. Farthing🇨🇦University of Saskatchewan
Resumen
El texto original del estudio, en el idioma en que se publicó.
Creatine supplementation in close proximity to resistance training may be an important strategy for increasing muscle mass and strength; however, it is unknown whether creatine supplementation before or after resistance training is more effective for aging adults. Using a double-blind, repeated measures design, older adults (50-71 years) were randomized to 1 of 3 groups: creatine before (CR-B: n = 15; creatine (0.1 g/kg) immediately before resistance training and placebo (0.1 g/kg cornstarch maltodextrin) immediately after resistance training), creatine after (CR-A: n = 12; placebo immediately before resistance training and creatine immediately after resistance training), or placebo (PLA: n = 12; placebo immediately before and immediately after resistance training) for 32 weeks. Prior to and following the study, body composition (lean tissue, fat mass; dual-energy X-ray absorptiometry) and muscle strength (1-repetition maximum leg press and chest press) were assessed. There was an increase over time for lean tissue mass and muscle strength and a decrease in fat mass (p < 0.05). CR-A resulted in greater improvements in lean tissue mass (Δ 3.0 ± 1.9 kg) compared with PLA (Δ 0.5 ± 2.1 kg; p < 0.025). Creatine supplementation, independent of the timing of ingestion, increased muscle strength more than placebo (leg press: CR-B, Δ 36.6 ± 26.6 kg; CR-A, Δ 40.8 ± 38.4 kg; PLA, Δ 5.6 ± 35.1 kg; chest press: CR-B, Δ 15.2 ± 13.0 kg; CR-A, Δ 15.7 ± 12.5 kg; PLA, Δ 1.9 ± 14.7 kg; p < 0.025). Compared with resistance training alone, creatine supplementation improves muscle strength, with greater gains in lean tissue mass resulting from post-exercise creatine supplementation.
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