A meta-analysis of risk of pregnancy loss and caffeine and coffee consumption during pregnancy
Li J, Zhao H, Song JM, Zhang J, Tang YL, Xin CM
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 58 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2015-05-14 · Int J Gynaecol Obstet · vol. 130 · número 2 · págs. 116–122
- Editorial
- Elsevier BV
- Citado
- 110 citas · más que el 97% de estudios similares · 6.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 42 trabajos
- Acceso
- De pago
- Áreas de investigación
- Coffee research and impacts · Gestational Diabetes Research and Management · Cancer Risks and Factors
- Palabras clave
- Medicine, Pregnancy, Caffeine, Obstetrics, Gynecology, Endocrinology
- MeSH
- humans, abortion, spontaneous, caffeine, risk, pregnancy, dose-response relationship, drug, coffee, female
6 autores
- Ji Li🇨🇳Anhui Medical University
- Hong Zhao
- Ju‐Min Song🇨🇳Kunming Medical University
- Jing Zhang🇨🇳Anhui Medical University; Second Affiliated Hospital of Anhui Medical University
- Y. P. Tang🇨🇳Anhui Medical University
- Chang‐Mao Xin🇨🇳 · autor de correspondenciaAnhui Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Previous reports of the relationship between pregnancy loss and caffeine/coffee consumption have been inconsistent.
Objectives
To evaluate the association between pregnancy loss and caffeine and coffee consumption.
Search strategy
PubMed was searched for reports published before September 2014, with the keywords "caffeine," "coffee," "beverage," "miscarriage," "spontaneous abortion," and "fetal loss."
Selection criteria
Case-control and cohort studies were included when they had been reported in English, the exposure of interest was caffeine/coffee consumption during pregnancy, the outcome of interest was spontaneous abortion or fetal death, and multivariate-adjusted odds ratios (ORs) or risk ratios were provided or could be calculated.
Data collection and analysis
Data were extracted and combined ORs calculated.
Main results
Overall, 26 studies were included (20 of caffeine and eight of coffee). After adjustment for heterogeneity, caffeine consumption was associated with an increased risk of pregnancy loss (OR 1.32, 95% confidence interval [CI] 1.24-1.40), as was coffee consumption (OR 1.11, 95% CI 1.02-1.21). A dose-response analysis suggested that risk of pregnancy loss rose by 19% for every increase in caffeine intake of 150 mg/day and by 8% for every increase in coffee intake of two cups per day.
Conclusions
Consumption of caffeine and coffee during pregnancy seems to increase the risk of pregnancy loss.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.