Effect of Creatine Loading on Oxygen Uptake during a 1-km Cycling Time Trial
De Andrade Nemezio KM, Bertuzzi R, Correia-Oliveira CR, Gualano B, Bishop DJ, Lima-Silva AE
Medicine and science in sports and exercise · 14 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2015-06-17 · Med Sci Sports Exerc · vol. 47 · número 12 · págs. 2660–2668
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 17 citas · más que el 68% de estudios similares · 0.6× el promedio de su campo
- Referencias
- 30 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Cardiovascular and exercise physiology
- Palabras clave
- creatine supplementation, creatine loading, oxygen consumption, oxygen deficit, cycling time trial, muscle recruitment, pacing strategy, plasma lactate, electromyography, amateur cyclists
- MeSH
- muscle, skeletal, humans, creatine, lactic acid, pulmonary ventilation, electromyography, body mass index, double-blind method, oxygen consumption, bicycling, dietary supplements, adult, male, body fat distribution
6 autores
- Kleiner Nemezio🇧🇷🇦🇺Universidade de São Paulo; Universidade Federal de Pernambuco; Victoria University
- Rômulo Bertuzzi🇧🇷Universidade de São Paulo
- Carlos Rafaell Correia‐Oliveira🇧🇷Universidade de São Paulo; Universidade Federal de Pernambuco
- Bruno Gualano🇧🇷Universidade de São Paulo
- David John Bishop🇦🇺Victoria University
- Adriano Eduardo Lima‐Silva🇧🇷Universidade Federal de Pernambuco
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
For the first time, we investigated the effects of altering cellular metabolic capacitance, via a 5-d creatine (Cr) loading protocol (20 g·d⁻¹), on oxygen uptake (VO2), accumulated oxygen deficit, muscle recruitment, and performance during a 1-km cycling time trial.
Methods
In a double-blind, randomized, placebo-controlled design, 19 amateur cyclists were allocated to a Cr (n = 10, VO2peak = 56.0 ± 7.8 mL·kg⁻¹·min⁻¹) or placebo (n = 9, VO2peak = 56.0 ± 8.4 mL·kg⁻¹·min⁻¹) group, and performed a 1-km cycling time trial before and after the supplementation period.
Results
Body mass was significantly increased in the Cr group (P < 0.05), but not in the placebo group. Participants adopted an "all-out" pacing strategy in both groups. However, Cr loading reduced VO2 immediately after the beginning (12th to 23th seconds), and this was accompanied by a reduced aerobic and increased anaerobic contribution. The VO2 mean response time was slower (pre: 17.2 ± 5.6 s vs post: 19.9 ± 4.6 s), the total O2 uptake was reduced (pre: 4.64 ± 0.59 L vs post: 4.47 ± 0.53 L), and the oxygen deficit was increased (pre: 0.82 ± 0.27 L vs post: 0.98 ± 0.25 L) after Cr loading. No differences were observed in the placebo group for these variables. Plasma lactate and integrated electromyography were not altered in either group, nor was the time to complete the trial (Cr group: pre: 89.1 ± 6.7 s vs post 89.1 ± 6.2 s and placebo group: pre 85.9 ± 4.9 s vs post 87.0 ± 5.4 s).
Conclusion
Cr loading slows the V˙O2 response and increases the anaerobic contribution during a 1-km cycling time trial.
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